Notificación FACEDRA basada en FHIR® R5 |
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Notificación FACEDRA basada en FHIR® R5 | - Local Development build (v0.1.1) built by the FHIR (HL7® FHIR® Standard) Build Tools. See the Directory of published versions

Resource Profile: Medicamento FACEDRA - Detailed Descriptions

Page standards status: Informative

Definitions for the medicamento-facedra resource profile

Guidance on how to interpret the contents of this table can be foundhere

0. Medication
Definition

This resource is primarily used for the identification and definition of a medication, including ingredients, for the purposes of prescribing, dispensing, and administering a medication as well as for making statements about medication use.

ShortDefinition of a Medication
Control0..*
Is Modifierfalse
Must Supportfalse
Summaryfalse
Invariantsdom-2: If the resource is contained in another resource, it SHALL NOT contain nested Resources (contained.contained.empty())
dom-3: If the resource is contained in another resource, it SHALL be referred to from elsewhere in the resource or SHALL refer to the containing resource (contained.where((('#'+id in (%resource.descendants().reference | %resource.descendants().ofType(canonical) | %resource.descendants().ofType(uri) | %resource.descendants().ofType(url))) or descendants().where(reference = '#').exists() or descendants().where(ofType(canonical) = '#').exists() or descendants().where(ofType(canonical) = '#').exists()).not()).trace('unmatched', id).empty())
dom-4: If a resource is contained in another resource, it SHALL NOT have a meta.versionId or a meta.lastUpdated (contained.meta.versionId.empty() and contained.meta.lastUpdated.empty())
dom-5: If a resource is contained in another resource, it SHALL NOT have a security label (contained.meta.security.empty())
dom-6: A resource should have narrative for robust management (text.`div`.exists())
2. Medication.implicitRules
Definition

A reference to a set of rules that were followed when the resource was constructed, and which must be understood when processing the content. Often, this is a reference to an implementation guide that defines the special rules along with other profiles etc.

ShortA set of rules under which this content was created
Comments

Asserting this rule set restricts the content to be only understood by a limited set of trading partners. This inherently limits the usefulness of the data in the long term. However, the existing health eco-system is highly fractured, and not yet ready to define, collect, and exchange data in a generally computable sense. Wherever possible, implementers and/or specification writers should avoid using this element. Often, when used, the URL is a reference to an implementation guide that defines these special rules as part of its narrative along with other profiles, value sets, etc.

Control0..1
Typeuri
Is Modifiertrue because This element is labeled as a modifier because the implicit rules may provide additional knowledge about the resource that modifies its meaning or interpretation
Primitive ValueThis primitive element may be present, or absent, or replaced by an extension
Must Supportfalse
Summarytrue
Invariantsele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count()))
4. Medication.contained
Definition

These resources do not have an independent existence apart from the resource that contains them - they cannot be identified independently, nor can they have their own independent transaction scope. This is allowed to be a Parameters resource if and only if it is referenced by a resource that provides context/meaning.

ShortContained, inline Resources
Comments

This should never be done when the content can be identified properly, as once identification is lost, it is extremely difficult (and context dependent) to restore it again. Contained resources may have profiles and tags in their meta elements, but SHALL NOT have security labels.

Control0..*
This element is affected by the following invariants: dom-2, dom-4, dom-3, dom-5
TypeResource
Is Modifierfalse
Must Supportfalse
Summaryfalse
Alternate Namesinline resources, anonymous resources, contained resources
6. Medication.modifierExtension
Definition

May be used to represent additional information that is not part of the basic definition of the resource and that modifies the understanding of the element that contains it and/or the understanding of the containing element's descendants. Usually modifier elements provide negation or qualification. To make the use of extensions safe and managable, there is a strict set of governance applied to the definition and use of extensions. Though any implementer is allowed to define an extension, there is a set of requirements that SHALL be met as part of the definition of the extension. Applications processing a resource are required to check for modifier extensions.

Modifier extensions SHALL NOT change the meaning of any elements on Resource or DomainResource (including cannot change the meaning of modifierExtension itself).

ShortExtensions that cannot be ignored
Comments

There can be no stigma associated with the use of extensions by any application, project, or standard - regardless of the institution or jurisdiction that uses or defines the extensions. The use of extensions is what allows the FHIR specification to retain a core level of simplicity for everyone.

Control0..*
TypeExtension
Is Modifiertrue because Modifier extensions are expected to modify the meaning or interpretation of the resource that contains them
Must Supportfalse
Summarytrue
Requirements

Modifier extensions allow for extensions that cannot be safely ignored to be clearly distinguished from the vast majority of extensions which can be safely ignored. This promotes interoperability by eliminating the need for implementers to prohibit the presence of extensions. For further information, see the definition of modifier extensions.

Alternate Namesextensions, user content
Invariantsele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count()))
ext-1: Must have either extensions or value[x], not both (extension.exists() != value.exists())
8. Medication.code
Definition

Nombre comercial del medicamento tal como lo reportó el notificador, junto con su identificación codificada (si está disponible) para facilitar la normalización y análisis de los datos de medicamentos en las notificaciones FACEDRA.


A code (or set of codes) that specify this medication, or a textual description if no code is available. Usage note: This could be a standard medication code such as a code from RxNorm, SNOMED CT, IDMP etc. It could also be a national or local formulary code, optionally with translations to other code systems.

ShortNombre e identificación del medicamentoCodes that identify this medication
Comments

Depending on the context of use, the code that was actually selected by the user (prescriber, dispenser, etc.) will have the coding.userSelected set to true. As described in the coding datatype: "A coding may be marked as a "userSelected" if a user selected the particular coded value in a user interface (e.g. the user selects an item in a pick-list). If a user selected coding exists, it is the preferred choice for performing translations etc. Other codes can only be literal translations to alternative code systems, or codes at a lower level of granularity (e.g. a generic code for a vendor-specific primary one).

Control10..1
BindingFor example codes, see SNOMEDCTMedicationCodeshttp://hl7.org/fhir/ValueSet/medication-codes|5.0.0
(example to http://hl7.org/fhir/ValueSet/medication-codes|5.0.0)

A coded concept that defines the type of a medication.

TypeCodeableConcept
Is Modifierfalse
Must Supportfalse
Summarytrue
Invariantsele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count()))
10. Medication.code.coding
Definition

Código del medicamento según la clasificación WHODrug, que puede corresponder al principio activo o al producto terminado, para facilitar la normalización y análisis de los datos de medicamentos en las notificaciones FACEDRA.


A reference to a code defined by a terminology system.

ShortCódigo WHODrug del principio activo o productoCode defined by a terminology system
Comments

Codes may be defined very casually in enumerations, or code lists, up to very formal definitions such as SNOMED CT - see the HL7 v3 Core Principles for more information. Ordering of codings is undefined and SHALL NOT be used to infer meaning. Generally, at most only one of the coding values will be labeled as UserSelected = true.

Control0..1*
BindingThe codes SHOULD be taken from For codes, see Medicamentos WHODrug Regional COMISCA
(preferred to https://hl7.comisca.org/fhir/ValueSet/whoDrug-regional-codes)
TypeCoding
Is Modifierfalse
Summarytrue
Requirements

Allows for alternative encodings within a code system, and translations to other code systems.

Invariantsele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count()))
12. Medication.code.coding.system
Definition

URI que identifica el sistema de codificación WHODrug utilizado para codificar el medicamento en las notificaciones FACEDRA.


The identification of the code system that defines the meaning of the symbol in the code.

ShortURI del sistema WHODrugIdentity of the terminology system
Comments

The URI may be an OID (urn:oid:...) or a UUID (urn:uuid:...). OIDs and UUIDs SHALL be references to the HL7 OID registry. Otherwise, the URI should come from HL7's list of FHIR defined special URIs or it should be an absolute reference to some definition that establishes the system clearly and unambiguously.

Control10..1
Typeuri
Is Modifierfalse
Primitive ValueThis primitive element may be present, or absent, or replaced by an extension
Summarytrue
Requirements

Need to be unambiguous about the source of the definition of the symbol.

Pattern Valuehttps://hl7.comisca.org/fhir/CodeSystem/whoDrug-regional
Invariantsele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count()))
14. Medication.code.coding.code
Definition

Código del medicamento según la clasificación WHODrug, que puede corresponder al principio activo o al producto terminado, para facilitar la normalización y análisis de los datos de medicamentos en las notificaciones FACEDRA.


A symbol in syntax defined by the system. The symbol may be a predefined code or an expression in a syntax defined by the coding system (e.g. post-coordination).

ShortCódigo WHODrugSymbol in syntax defined by the system
Control10..1
This element is affected by the following invariants: cod-1
Typecode
Is Modifierfalse
Primitive ValueThis primitive element may be present, or absent, or replaced by an extension
Summarytrue
Requirements

Need to refer to a particular code in the system.

Invariantsele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count()))
16. Medication.code.coding.display
Definition

Nombre del medicamento según la clasificación WHODrug, que puede corresponder al principio activo o al producto terminado, para facilitar la normalización y análisis de los datos de medicamentos en las notificaciones FACEDRA.


A representation of the meaning of the code in the system, following the rules of the system.

ShortNombre normalizado (WHODrug)Representation defined by the system
Control10..1
This element is affected by the following invariants: cod-1
Typestring
Is Modifierfalse
Primitive ValueThis primitive element may be present, or absent, or replaced by an extension
Summarytrue
Requirements

Need to be able to carry a human-readable meaning of the code for readers that do not know the system.

Invariantsele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count()))
18. Medication.code.text
Definition

Nombre del medicamento tal como lo reportó el notificador, sin normalizar ni codificar, para preservar la información original proporcionada en la notificación FACEDRA.


A human language representation of the concept as seen/selected/uttered by the user who entered the data and/or which represents the intended meaning of the user.

ShortNombre tal como lo reportó el notificador (nombre comercial)Plain text representation of the concept
Comments

Very often the text is the same as a displayName of one of the codings.

Control10..1
Typestring
Is Modifierfalse
Primitive ValueThis primitive element may be present, or absent, or replaced by an extension
Summarytrue
Requirements

The codes from the terminologies do not always capture the correct meaning with all the nuances of the human using them, or sometimes there is no appropriate code at all. In these cases, the text is used to capture the full meaning of the source.

Invariantsele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count()))
20. Medication.status
Definition

Estado del medicamento reportado en las notificaciones FACEDRA, que indica si el medicamento está actualmente en uso (active) o si ha sido retirado del mercado o descontinuado (inactive) para facilitar la normalización y análisis de los datos de medicamentos en las notificaciones FACEDRA.


A code to indicate if the medication is in active use.

ShortEstado del medicamento: active | inactiveactive | inactive | entered-in-error
Comments

This status is intended to identify if the medication in a local system is in active use within a drug database or inventory. For example, a pharmacy system may create a new drug file record for a compounded product "ABC Hospital Special Cream" with an active status. At some point in the future, it may be determined that the drug record was created with an error and the status is changed to "entered in error". This status is not intended to specify if a medication is part of a particular formulary. It is possible that the drug record may be referenced by multiple formularies or catalogues and each of those entries would have a separate status.

Control0..1
BindingThe codes SHALL be taken from MedicationStatusCodeshttp://hl7.org/fhir/ValueSet/medication-status|5.0.0
(required to http://hl7.org/fhir/ValueSet/medication-status|5.0.0)

A coded concept defining if the medication is in active use.

Typecode
Is Modifiertrue because This element changes the interpretation of all descriptive attributes.
Primitive ValueThis primitive element may be present, or absent, or replaced by an extension
Must Supportfalse
Summarytrue
Invariantsele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count()))
facedra-med-status-activo-inactivo: Cuando se informa status, solo se permiten los valores active o inactive. ($this = 'active' or $this = 'inactive')
22. Medication.marketingAuthorizationHolder
Definition

Laboratorio titular del registro sanitario del medicamento reportado en las notificaciones FACEDRA, para facilitar la identificación y seguimiento de los responsables de la autorización de los medicamentos en las notificaciones FACEDRA.


The company or other legal entity that has authorization, from the appropriate drug regulatory authority, to market a medicine in one or more jurisdictions. Typically abbreviated MAH.Note: The MAH may manufacture the product and may also contract the manufacturing of the product to one or more companies (organizations).

ShortLaboratorio titular del registro sanitarioOrganization that has authorization to market medication
Control0..1
TypeReference(Organization)
Is Modifierfalse
Must Supportfalse
Summarytrue
Invariantsele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count()))
24. Medication.doseForm
Definition

Forma farmacéutica del medicamento reportado en las notificaciones FACEDRA, que describe la presentación física del medicamento (por ejemplo, tableta, cápsula, inyectable, etc.) para facilitar la normalización y análisis de los datos de medicamentos en las notificaciones FACEDRA.


Describes the form of the item. Powder; tablets; capsule.

ShortForma farmacéutica (tableta, cápsula, inyectable, etc.)powder | tablets | capsule +
Comments

When Medication is referenced from MedicationRequest, this is the ordered form. When Medication is referenced within MedicationDispense, this is the dispensed form. When Medication is referenced within MedicationAdministration, this is administered form.

Control0..1
BindingFor example codes, see SNOMEDCTFormCodeshttp://hl7.org/fhir/ValueSet/medication-form-codes|5.0.0
(example to http://hl7.org/fhir/ValueSet/medication-form-codes|5.0.0)

A coded concept defining the form of a medication.

TypeCodeableConcept
Is Modifierfalse
Must Supportfalse
Summaryfalse
Invariantsele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count()))
26. Medication.doseForm.coding
Definition

Código que representa la forma farmacéutica del medicamento reportado en las notificaciones FACEDRA, utilizando un sistema de codificación estándar para facilitar la normalización y análisis de los datos de medicamentos en las notificaciones FACEDRA.


A reference to a code defined by a terminology system.

ShortCódigo de la forma farmacéuticaCode defined by a terminology system
Comments

Codes may be defined very casually in enumerations, or code lists, up to very formal definitions such as SNOMED CT - see the HL7 v3 Core Principles for more information. Ordering of codings is undefined and SHALL NOT be used to infer meaning. Generally, at most only one of the coding values will be labeled as UserSelected = true.

Control0..1*
TypeCoding
Is Modifierfalse
Summarytrue
Requirements

Allows for alternative encodings within a code system, and translations to other code systems.

Invariantsele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count()))
28. Medication.doseForm.coding.system
Definition

The identification of the code system that defines the meaning of the symbol in the code.

ShortIdentity of the terminology system
Comments

The URI may be an OID (urn:oid:...) or a UUID (urn:uuid:...). OIDs and UUIDs SHALL be references to the HL7 OID registry. Otherwise, the URI should come from HL7's list of FHIR defined special URIs or it should be an absolute reference to some definition that establishes the system clearly and unambiguously.

Control10..1
Typeuri
Is Modifierfalse
Primitive ValueThis primitive element may be present, or absent, or replaced by an extension
Summarytrue
Requirements

Need to be unambiguous about the source of the definition of the symbol.

Invariantsele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count()))
30. Medication.doseForm.coding.code
Definition

Código que representa la forma farmacéutica del medicamento reportado en las notificaciones FACEDRA, utilizando un sistema de codificación estándar para facilitar la normalización y análisis de los datos de medicamentos en las notificaciones FACEDRA.


A symbol in syntax defined by the system. The symbol may be a predefined code or an expression in a syntax defined by the coding system (e.g. post-coordination).

ShortCódigo de la forma farmacéuticaSymbol in syntax defined by the system
Control10..1
This element is affected by the following invariants: cod-1
Typecode
Is Modifierfalse
Primitive ValueThis primitive element may be present, or absent, or replaced by an extension
Summarytrue
Requirements

Need to refer to a particular code in the system.

Invariantsele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count()))
32. Medication.doseForm.coding.display
Definition

Nombre de la forma farmacéutica del medicamento reportado en las notificaciones FACEDRA, utilizando un sistema de codificación estándar para facilitar la normalización y análisis de los datos de medicamentos en las notificaciones FACEDRA.


A representation of the meaning of the code in the system, following the rules of the system.

ShortNombre de la forma farmacéuticaRepresentation defined by the system
Control10..1
This element is affected by the following invariants: cod-1
Typestring
Is Modifierfalse
Primitive ValueThis primitive element may be present, or absent, or replaced by an extension
Summarytrue
Requirements

Need to be able to carry a human-readable meaning of the code for readers that do not know the system.

Invariantsele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count()))
34. Medication.ingredient
Definition

Información detallada sobre el o los principios activos presentes en el medicamento reportado en las notificaciones FACEDRA, incluyendo su identificación codificada (si está disponible), concentración, forma farmacéutica, lote, fecha de caducidad y titular de venta, para facilitar la normalización y análisis de los datos de medicamentos en las notificaciones FACEDRA.


Identifies a particular constituent of interest in the product.

ShortPrincipio(s) activo(s) del medicamentoActive or inactive ingredient
Comments

The ingredients need not be a complete list. If an ingredient is not specified, this does not indicate whether an ingredient is present or absent. If an ingredient is specified it does not mean that all ingredients are specified. It is possible to specify both inactive and active ingredients.

Control0..*
TypeBackboneElement
Is Modifierfalse
Must Supportfalse
Summaryfalse
Invariantsele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count()))
36. Medication.ingredient.modifierExtension
Definition

May be used to represent additional information that is not part of the basic definition of the element and that modifies the understanding of the element in which it is contained and/or the understanding of the containing element's descendants. Usually modifier elements provide negation or qualification. To make the use of extensions safe and managable, there is a strict set of governance applied to the definition and use of extensions. Though any implementer can define an extension, there is a set of requirements that SHALL be met as part of the definition of the extension. Applications processing a resource are required to check for modifier extensions.

Modifier extensions SHALL NOT change the meaning of any elements on Resource or DomainResource (including cannot change the meaning of modifierExtension itself).

ShortExtensions that cannot be ignored even if unrecognized
Comments

There can be no stigma associated with the use of extensions by any application, project, or standard - regardless of the institution or jurisdiction that uses or defines the extensions. The use of extensions is what allows the FHIR specification to retain a core level of simplicity for everyone.

Control0..*
TypeExtension
Is Modifiertrue because Modifier extensions are expected to modify the meaning or interpretation of the element that contains them
Summarytrue
Requirements

Modifier extensions allow for extensions that cannot be safely ignored to be clearly distinguished from the vast majority of extensions which can be safely ignored. This promotes interoperability by eliminating the need for implementers to prohibit the presence of extensions. For further information, see the definition of modifier extensions.

Alternate Namesextensions, user content, modifiers
Invariantsele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count()))
ext-1: Must have either extensions or value[x], not both (extension.exists() != value.exists())
38. Medication.ingredient.item
Definition

Identificación codificada del principio activo presente en el medicamento reportado en las notificaciones FACEDRA, utilizando la clasificación WHODrug para facilitar la normalización y análisis de los datos de medicamentos en las notificaciones FACEDRA.


The ingredient (substance or medication) that the ingredient.strength relates to. This is represented as a concept from a code system or described in another resource (Substance or Medication).

ShortSustancia activa codificada con WHODrugThe ingredient (substance or medication) that the ingredient.strength relates to
Control1..1
BindingFor example codes, see SNOMEDCTMedicationCodeshttp://hl7.org/fhir/ValueSet/medication-codes|5.0.0
(example to http://hl7.org/fhir/ValueSet/medication-codes|5.0.0)
TypeCodeableReference(Substance, Medication)
Is Modifierfalse
Must Supportfalse
Summaryfalse
Requirements

The ingredient may reference a substance (for example, amoxicillin) or another medication (for example in the case of a compounded product, Glaxal Base).

Invariantsele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count()))
40. Medication.ingredient.strength[x]
Definition

Specifies how many (or how much) of the items there are in this Medication. For example, 250 mg per tablet. This is expressed as a ratio where the numerator is 250mg and the denominator is 1 tablet but can also be expressed a quantity when the denominator is assumed to be 1 tablet.

ShortQuantity of ingredient present
Control0..1
BindingThe codes SHOULD be taken from MedicationIngredientStrengthCodeshttp://hl7.org/fhir/ValueSet/medication-ingredientstrength|5.0.0
(preferred to http://hl7.org/fhir/ValueSet/medication-ingredientstrength|5.0.0)

A coded concpet defining the strength of an ingredient.

TypeChoice of: Ratio, CodeableConcept, Quantity
[x] NoteSeeChoice of Data Typesfor further information about how to use [x]
Is Modifierfalse
Must Supportfalse
Summaryfalse
Invariantsele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count()))
SlicingThis element introduces a set of slices on Medication.ingredient.strength[x]. The slices areUnordered and Open, and can be differentiated using the following discriminators:
  • type @ $this
  • 42. Medication.ingredient.strength[x]:strengthRatio
    Slice NamestrengthRatio
    Definition

    Concentración del principio activo presente en el medicamento reportado en las notificaciones FACEDRA, expresada como una proporción (numerador/denominador) para facilitar la normalización y análisis de los datos de medicamentos en las notificaciones FACEDRA.


    Specifies how many (or how much) of the items there are in this Medication. For example, 250 mg per tablet. This is expressed as a ratio where the numerator is 250mg and the denominator is 1 tablet but can also be expressed a quantity when the denominator is assumed to be 1 tablet.

    ShortConcentración del ingrediente activoQuantity of ingredient present
    Control0..1
    TypeRatio, Quantity, CodeableConcept
    [x] NoteSeeChoice of Data Typesfor further information about how to use [x]
    Is Modifierfalse
    Must Supportfalse
    Summaryfalse
    Invariantsele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count()))
    44. Medication.ingredient.strength[x]:strengthRatio.numerator
    Definition

    Valor numérico del numerador en la proporción que representa la concentración del principio activo en el medicamento reportado en las notificaciones FACEDRA.


    The value of the numerator.

    ShortNumerador de la concentración del principio activoNumerator value
    Control10..1
    This element is affected by the following invariants: rat-1
    TypeQuantity
    Is Modifierfalse
    Summarytrue
    Invariantsele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count()))
    46. Medication.ingredient.strength[x]:strengthRatio.numerator.value
    Definition

    Valor numérico del numerador en la proporción que representa la concentración del principio activo en el medicamento reportado en las notificaciones FACEDRA.


    The value of the measured amount. The value includes an implicit precision in the presentation of the value.

    ShortValor numérico del numeradorNumerical value (with implicit precision)
    Comments

    The implicit precision in the value should always be honored. Monetary values have their own rules for handling precision (refer to standard accounting text books).

    Control10..1
    Typedecimal
    Is Modifierfalse
    Primitive ValueThis primitive element may be present, or absent, or replaced by an extension
    Summarytrue
    Requirements

    Precision is handled implicitly in almost all cases of measurement.

    Invariantsele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count()))
    48. Medication.ingredient.strength[x]:strengthRatio.numerator.comparator
    Definition

    How the value should be understood and represented - whether the actual value is greater or less than the stated value due to measurement issues; e.g. if the comparator is "<" , then the real value is < stated value.

    Short< | <= | >= | > | ad - how to understand the value
    Control0..1
    BindingThe codes SHALL be taken from QuantityComparatorhttp://hl7.org/fhir/ValueSet/quantity-comparator|5.0.0
    (required to http://hl7.org/fhir/ValueSet/quantity-comparator|5.0.0)

    How the Quantity should be understood and represented.

    Typecode
    Is Modifiertrue because This is labeled as "Is Modifier" because the comparator modifies the interpretation of the value significantly. If there is no comparator, then there is no modification of the value
    Primitive ValueThis primitive element may be present, or absent, or replaced by an extension
    Summarytrue
    Requirements

    Need a framework for handling measures where the value is <5ug/L or >400mg/L due to the limitations of measuring methodology.

    Meaning if MissingIf there is no comparator, then there is no modification of the value
    Invariantsele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count()))
    50. Medication.ingredient.strength[x]:strengthRatio.numerator.unit
    Definition

    Unidad de medida del numerador en la proporción que representa la concentración del principio activo en el medicamento reportado en las notificaciones FACEDRA, utilizando las unidades de medida estándar definidas en el sistema de codificación WHODrug para facilitar la normalización y análisis de los datos de medicamentos en las notificaciones FACEDRA.


    A human-readable form of the unit.

    ShortUnidad de medida del numeradorUnit representation
    Control10..1
    Typestring
    Is Modifierfalse
    Primitive ValueThis primitive element may be present, or absent, or replaced by an extension
    Summarytrue
    Requirements

    There are many representations for units of measure and in many contexts, particular representations are fixed and required. I.e. mcg for micrograms.

    Invariantsele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count()))
    52. Medication.ingredient.strength[x]:strengthRatio.numerator.system
    Definition

    URI que identifica el sistema de codificación de unidades de medida utilizado para codificar la unidad del numerador en la proporción que representa la concentración del principio activo en el medicamento reportado en las notificaciones FACEDRA, utilizando las unidades de medida estándar definidas en el sistema de codificación WHODrug para facilitar la normalización y análisis de los datos de medicamentos en las notificaciones FACEDRA.


    The identification of the system that provides the coded form of the unit.

    ShortURI del sistema de unidades para el numeradorSystem that defines coded unit form
    Control10..1
    This element is affected by the following invariants: qty-3
    Typeuri
    Is Modifierfalse
    Primitive ValueThis primitive element may be present, or absent, or replaced by an extension
    Summarytrue
    Requirements

    Need to know the system that defines the coded form of the unit.

    Pattern Valuehttp://unitsofmeasure.org
    Invariantsele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count()))
    54. Medication.ingredient.strength[x]:strengthRatio.numerator.code
    Definition

    Código de la unidad de medida del numerador en la proporción que representa la concentración del principio activo en el medicamento reportado en las notificaciones FACEDRA, utilizando las unidades de medida estándar definidas en el sistema de codificación WHODrug para facilitar la normalización y análisis de los datos de medicamentos en las notificaciones FACEDRA.


    A computer processable form of the unit in some unit representation system.

    ShortCódigo de la unidad del numeradorCoded form of the unit
    Comments

    The preferred system is UCUM, but SNOMED CT can also be used (for customary units) or ISO 4217 for currency. The context of use may additionally require a code from a particular system.

    Control10..1
    This element is affected by the following invariants: qty-3
    Typecode
    Is Modifierfalse
    Primitive ValueThis primitive element may be present, or absent, or replaced by an extension
    Summarytrue
    Requirements

    Need a computable form of the unit that is fixed across all forms. UCUM provides this for quantities, but SNOMED CT provides many units of interest.

    Invariantsele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count()))
    56. Medication.ingredient.strength[x]:strengthRatio.denominator
    Definition

    Valor numérico del denominador en la proporción que representa la concentración del principio activo en el medicamento reportado en las notificaciones FACEDRA.


    The value of the denominator.

    ShortDenominador de la concentración del principio activoDenominator value
    Control10..1
    This element is affected by the following invariants: rat-1
    TypeQuantity(SimpleQuantity)
    Is Modifierfalse
    Summarytrue
    Invariantsele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count()))
    58. Medication.ingredient.strength[x]:strengthRatio.denominator.value
    Definition

    Valor numérico del denominador en la proporción que representa la concentración del principio activo en el medicamento reportado en las notificaciones FACEDRA.


    The value of the measured amount. The value includes an implicit precision in the presentation of the value.

    ShortValor numérico del denominadorNumerical value (with implicit precision)
    Comments

    The implicit precision in the value should always be honored. Monetary values have their own rules for handling precision (refer to standard accounting text books).

    Control10..1
    Typedecimal
    Is Modifierfalse
    Primitive ValueThis primitive element may be present, or absent, or replaced by an extension
    Summarytrue
    Requirements

    Precision is handled implicitly in almost all cases of measurement.

    Invariantsele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count()))
    60. Medication.ingredient.strength[x]:strengthRatio.denominator.comparator
    Definition

    Not allowed to be used in this context


    How the value should be understood and represented - whether the actual value is greater or less than the stated value due to measurement issues; e.g. if the comparator is "<" , then the real value is < stated value.

    Short< | <= | >= | > | ad - how to understand the value
    Control0..01
    BindingThe codes SHALL be taken from QuantityComparatorhttp://hl7.org/fhir/ValueSet/quantity-comparator|5.0.0
    (required to http://hl7.org/fhir/ValueSet/quantity-comparator|5.0.0)

    How the Quantity should be understood and represented.

    Typecode
    Is Modifiertrue because This is labeled as "Is Modifier" because the comparator modifies the interpretation of the value significantly. If there is no comparator, then there is no modification of the value
    Primitive ValueThis primitive element may be present, or absent, or replaced by an extension
    Summarytrue
    Requirements

    Need a framework for handling measures where the value is <5ug/L or >400mg/L due to the limitations of measuring methodology.

    Meaning if MissingIf there is no comparator, then there is no modification of the value
    Invariantsele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count()))
    62. Medication.ingredient.strength[x]:strengthRatio.denominator.unit
    Definition

    Unidad de medida del denominador en la proporción que representa la concentración del principio activo en el medicamento reportado en las notificaciones FACEDRA, utilizando las unidades de medida estándar definidas en el sistema de codificación WHODrug para facilitar la normalización y análisis de los datos de medicamentos en las notificaciones FACEDRA.


    A human-readable form of the unit.

    ShortUnidad de medida del denominadorUnit representation
    Control10..1
    Typestring
    Is Modifierfalse
    Primitive ValueThis primitive element may be present, or absent, or replaced by an extension
    Summarytrue
    Requirements

    There are many representations for units of measure and in many contexts, particular representations are fixed and required. I.e. mcg for micrograms.

    Invariantsele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count()))
    64. Medication.ingredient.strength[x]:strengthRatio.denominator.system
    Definition

    URI que identifica el sistema de codificación de unidades de medida utilizado para codificar la unidad del denominador en la proporción que representa la concentración del principio activo en el medicamento reportado en las notificaciones FACEDRA, utilizando las unidades de medida estándar definidas en el sistema de codificación WHODrug para facilitar la normalización y análisis de los datos de medicamentos en las notificaciones FACEDRA.


    The identification of the system that provides the coded form of the unit.

    ShortURI del sistema de unidades para el denominadorSystem that defines coded unit form
    Control10..1
    This element is affected by the following invariants: qty-3
    Typeuri
    Is Modifierfalse
    Primitive ValueThis primitive element may be present, or absent, or replaced by an extension
    Summarytrue
    Requirements

    Need to know the system that defines the coded form of the unit.

    Pattern Valuehttp://unitsofmeasure.org
    Invariantsele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count()))
    66. Medication.ingredient.strength[x]:strengthRatio.denominator.code
    Definition

    Código de la unidad de medida del denominador en la proporción que representa la concentración del principio activo en el medicamento reportado en las notificaciones FACEDRA, utilizando las unidades de medida estándar definidas en el sistema de codificación WHODrug para facilitar la normalización y análisis de los datos de medicamentos en las notificaciones FACEDRA.


    A computer processable form of the unit in some unit representation system.

    ShortCódigo de la unidad del denominadorCoded form of the unit
    Comments

    The preferred system is UCUM, but SNOMED CT can also be used (for customary units) or ISO 4217 for currency. The context of use may additionally require a code from a particular system.

    Control10..1
    This element is affected by the following invariants: qty-3
    Typecode
    Is Modifierfalse
    Primitive ValueThis primitive element may be present, or absent, or replaced by an extension
    Summarytrue
    Requirements

    Need a computable form of the unit that is fixed across all forms. UCUM provides this for quantities, but SNOMED CT provides many units of interest.

    Invariantsele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count()))
    68. Medication.batch
    Definition

    Información sobre el lote y la fecha de caducidad del medicamento reportado en las notificaciones FACEDRA, para facilitar la normalización y análisis de los datos de medicamentos en las notificaciones FACEDRA, así como para apoyar la identificación de posibles problemas relacionados con lotes específicos de medicamentos en las notificaciones FACEDRA.


    Information that only applies to packages (not products).

    ShortInformación de lote y caducidad del medicamentoDetails about packaged medications
    Control0..1
    TypeBackboneElement
    Is Modifierfalse
    Must Supportfalse
    Summaryfalse
    Invariantsele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count()))
    70. Medication.batch.modifierExtension
    Definition

    May be used to represent additional information that is not part of the basic definition of the element and that modifies the understanding of the element in which it is contained and/or the understanding of the containing element's descendants. Usually modifier elements provide negation or qualification. To make the use of extensions safe and managable, there is a strict set of governance applied to the definition and use of extensions. Though any implementer can define an extension, there is a set of requirements that SHALL be met as part of the definition of the extension. Applications processing a resource are required to check for modifier extensions.

    Modifier extensions SHALL NOT change the meaning of any elements on Resource or DomainResource (including cannot change the meaning of modifierExtension itself).

    ShortExtensions that cannot be ignored even if unrecognized
    Comments

    There can be no stigma associated with the use of extensions by any application, project, or standard - regardless of the institution or jurisdiction that uses or defines the extensions. The use of extensions is what allows the FHIR specification to retain a core level of simplicity for everyone.

    Control0..*
    TypeExtension
    Is Modifiertrue because Modifier extensions are expected to modify the meaning or interpretation of the element that contains them
    Summarytrue
    Requirements

    Modifier extensions allow for extensions that cannot be safely ignored to be clearly distinguished from the vast majority of extensions which can be safely ignored. This promotes interoperability by eliminating the need for implementers to prohibit the presence of extensions. For further information, see the definition of modifier extensions.

    Alternate Namesextensions, user content, modifiers
    Invariantsele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count()))
    ext-1: Must have either extensions or value[x], not both (extension.exists() != value.exists())
    72. Medication.batch.lotNumber
    Definition

    Número de lote del medicamento reportado en las notificaciones FACEDRA, impreso en el empaque, para facilitar la identificación y seguimiento de lotes específicos en las notificaciones FACEDRA.


    The assigned lot number of a batch of the specified product.

    ShortNúmero de lote impreso en el empaqueIdentifier assigned to batch
    Control0..1
    Typestring
    Is Modifierfalse
    Primitive ValueThis primitive element may be present, or absent, or replaced by an extension
    Must Supportfalse
    Summaryfalse
    Invariantsele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count()))
    74. Medication.batch.expirationDate
    Definition

    Fecha de caducidad del medicamento reportado en las notificaciones FACEDRA, en formato MM/AAAA, para facilitar la identificación y seguimiento de la validez de los medicamentos en las notificaciones FACEDRA.


    When this specific batch of product will expire.

    ShortFecha de caducidad (formato MM/AAAA)When batch will expire
    Control0..1
    TypedateTime
    Is Modifierfalse
    Primitive ValueThis primitive element may be present, or absent, or replaced by an extension
    Must Supportfalse
    Summaryfalse
    Invariantsele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count()))

    Guidance on how to interpret the contents of this table can be foundhere

    0. Medication
    2. Medication.code
    Definition

    Nombre comercial del medicamento tal como lo reportó el notificador, junto con su identificación codificada (si está disponible) para facilitar la normalización y análisis de los datos de medicamentos en las notificaciones FACEDRA.

    ShortNombre e identificación del medicamento
    Control1..?
    4. Medication.code.coding
    Definition

    Código del medicamento según la clasificación WHODrug, que puede corresponder al principio activo o al producto terminado, para facilitar la normalización y análisis de los datos de medicamentos en las notificaciones FACEDRA.

    ShortCódigo WHODrug del principio activo o producto
    Control0..1
    BindingThe codes SHOULD be taken from Medicamentos WHODrug Regional COMISCA
    (preferred to https://hl7.comisca.org/fhir/ValueSet/whoDrug-regional-codes)
    6. Medication.code.coding.system
    Definition

    URI que identifica el sistema de codificación WHODrug utilizado para codificar el medicamento en las notificaciones FACEDRA.

    ShortURI del sistema WHODrug
    Control1..?
    Pattern Valuehttps://hl7.comisca.org/fhir/CodeSystem/whoDrug-regional
    8. Medication.code.coding.code
    Definition

    Código del medicamento según la clasificación WHODrug, que puede corresponder al principio activo o al producto terminado, para facilitar la normalización y análisis de los datos de medicamentos en las notificaciones FACEDRA.

    ShortCódigo WHODrug
    Control1..?
    10. Medication.code.coding.display
    Definition

    Nombre del medicamento según la clasificación WHODrug, que puede corresponder al principio activo o al producto terminado, para facilitar la normalización y análisis de los datos de medicamentos en las notificaciones FACEDRA.

    ShortNombre normalizado (WHODrug)
    Control1..?
    12. Medication.code.text
    Definition

    Nombre del medicamento tal como lo reportó el notificador, sin normalizar ni codificar, para preservar la información original proporcionada en la notificación FACEDRA.

    ShortNombre tal como lo reportó el notificador (nombre comercial)
    Control1..?
    14. Medication.status
    Definition

    Estado del medicamento reportado en las notificaciones FACEDRA, que indica si el medicamento está actualmente en uso (active) o si ha sido retirado del mercado o descontinuado (inactive) para facilitar la normalización y análisis de los datos de medicamentos en las notificaciones FACEDRA.

    ShortEstado del medicamento: active | inactive
    Invariantsfacedra-med-status-activo-inactivo: Cuando se informa status, solo se permiten los valores active o inactive. ($this = 'active' or $this = 'inactive')
    16. Medication.marketingAuthorizationHolder
    Definition

    Laboratorio titular del registro sanitario del medicamento reportado en las notificaciones FACEDRA, para facilitar la identificación y seguimiento de los responsables de la autorización de los medicamentos en las notificaciones FACEDRA.

    ShortLaboratorio titular del registro sanitario
    18. Medication.doseForm
    Definition

    Forma farmacéutica del medicamento reportado en las notificaciones FACEDRA, que describe la presentación física del medicamento (por ejemplo, tableta, cápsula, inyectable, etc.) para facilitar la normalización y análisis de los datos de medicamentos en las notificaciones FACEDRA.

    ShortForma farmacéutica (tableta, cápsula, inyectable, etc.)
    20. Medication.doseForm.coding
    Definition

    Código que representa la forma farmacéutica del medicamento reportado en las notificaciones FACEDRA, utilizando un sistema de codificación estándar para facilitar la normalización y análisis de los datos de medicamentos en las notificaciones FACEDRA.

    ShortCódigo de la forma farmacéutica
    Control0..1
    22. Medication.doseForm.coding.system
    Control1..?
    24. Medication.doseForm.coding.code
    Definition

    Código que representa la forma farmacéutica del medicamento reportado en las notificaciones FACEDRA, utilizando un sistema de codificación estándar para facilitar la normalización y análisis de los datos de medicamentos en las notificaciones FACEDRA.

    ShortCódigo de la forma farmacéutica
    Control1..?
    26. Medication.doseForm.coding.display
    Definition

    Nombre de la forma farmacéutica del medicamento reportado en las notificaciones FACEDRA, utilizando un sistema de codificación estándar para facilitar la normalización y análisis de los datos de medicamentos en las notificaciones FACEDRA.

    ShortNombre de la forma farmacéutica
    Control1..?
    28. Medication.ingredient
    Definition

    Información detallada sobre el o los principios activos presentes en el medicamento reportado en las notificaciones FACEDRA, incluyendo su identificación codificada (si está disponible), concentración, forma farmacéutica, lote, fecha de caducidad y titular de venta, para facilitar la normalización y análisis de los datos de medicamentos en las notificaciones FACEDRA.

    ShortPrincipio(s) activo(s) del medicamento
    30. Medication.ingredient.item
    Definition

    Identificación codificada del principio activo presente en el medicamento reportado en las notificaciones FACEDRA, utilizando la clasificación WHODrug para facilitar la normalización y análisis de los datos de medicamentos en las notificaciones FACEDRA.

    ShortSustancia activa codificada con WHODrug
    32. Medication.ingredient.item.concept
    34. Medication.ingredient.item.concept.coding
    Control0..1
    36. Medication.ingredient.item.concept.coding.system
    Definition

    URI que identifica el sistema de codificación WHODrug utilizado para codificar el principio activo en las notificaciones FACEDRA.

    ShortURI del sistema WHODrug
    Control1..?
    Pattern Valuehttps://hl7.comisca.org/fhir/CodeSystem/whoDrug-regional
    38. Medication.ingredient.item.concept.coding.code
    Control1..?
    40. Medication.ingredient.item.concept.coding.display
    Control1..?
    42. Medication.ingredient.item.concept.text
    Definition

    Nombre del principio activo en texto libre, tal como lo reportó el notificador en las notificaciones FACEDRA, para preservar la información original proporcionada y facilitar la normalización y análisis de los datos de medicamentos en las notificaciones FACEDRA.

    ShortNombre de la sustancia en texto libre
    44. Medication.ingredient.strength[x]
    [x] NoteSeeChoice of Data Typesfor further information about how to use [x]
    SlicingThis element introduces a set of slices on Medication.ingredient.strength[x]. The slices areUnordered and Open, and can be differentiated using the following discriminators:
    • type @ $this
    • 46. Medication.ingredient.strength[x]:strengthRatio
      Slice NamestrengthRatio
      Definition

      Concentración del principio activo presente en el medicamento reportado en las notificaciones FACEDRA, expresada como una proporción (numerador/denominador) para facilitar la normalización y análisis de los datos de medicamentos en las notificaciones FACEDRA.

      ShortConcentración del ingrediente activo
      Control0..1
      TypeRatio
      [x] NoteSeeChoice of Data Typesfor further information about how to use [x]
      48. Medication.ingredient.strength[x]:strengthRatio.numerator
      Definition

      Valor numérico del numerador en la proporción que representa la concentración del principio activo en el medicamento reportado en las notificaciones FACEDRA.

      ShortNumerador de la concentración del principio activo
      Control1..?
      50. Medication.ingredient.strength[x]:strengthRatio.numerator.value
      Definition

      Valor numérico del numerador en la proporción que representa la concentración del principio activo en el medicamento reportado en las notificaciones FACEDRA.

      ShortValor numérico del numerador
      Control1..?
      52. Medication.ingredient.strength[x]:strengthRatio.numerator.unit
      Definition

      Unidad de medida del numerador en la proporción que representa la concentración del principio activo en el medicamento reportado en las notificaciones FACEDRA, utilizando las unidades de medida estándar definidas en el sistema de codificación WHODrug para facilitar la normalización y análisis de los datos de medicamentos en las notificaciones FACEDRA.

      ShortUnidad de medida del numerador
      Control1..?
      54. Medication.ingredient.strength[x]:strengthRatio.numerator.system
      Definition

      URI que identifica el sistema de codificación de unidades de medida utilizado para codificar la unidad del numerador en la proporción que representa la concentración del principio activo en el medicamento reportado en las notificaciones FACEDRA, utilizando las unidades de medida estándar definidas en el sistema de codificación WHODrug para facilitar la normalización y análisis de los datos de medicamentos en las notificaciones FACEDRA.

      ShortURI del sistema de unidades para el numerador
      Control1..?
      Pattern Valuehttp://unitsofmeasure.org
      56. Medication.ingredient.strength[x]:strengthRatio.numerator.code
      Definition

      Código de la unidad de medida del numerador en la proporción que representa la concentración del principio activo en el medicamento reportado en las notificaciones FACEDRA, utilizando las unidades de medida estándar definidas en el sistema de codificación WHODrug para facilitar la normalización y análisis de los datos de medicamentos en las notificaciones FACEDRA.

      ShortCódigo de la unidad del numerador
      Control1..?
      58. Medication.ingredient.strength[x]:strengthRatio.denominator
      Definition

      Valor numérico del denominador en la proporción que representa la concentración del principio activo en el medicamento reportado en las notificaciones FACEDRA.

      ShortDenominador de la concentración del principio activo
      Control1..?
      60. Medication.ingredient.strength[x]:strengthRatio.denominator.value
      Definition

      Valor numérico del denominador en la proporción que representa la concentración del principio activo en el medicamento reportado en las notificaciones FACEDRA.

      ShortValor numérico del denominador
      Control1..?
      62. Medication.ingredient.strength[x]:strengthRatio.denominator.unit
      Definition

      Unidad de medida del denominador en la proporción que representa la concentración del principio activo en el medicamento reportado en las notificaciones FACEDRA, utilizando las unidades de medida estándar definidas en el sistema de codificación WHODrug para facilitar la normalización y análisis de los datos de medicamentos en las notificaciones FACEDRA.

      ShortUnidad de medida del denominador
      Control1..?
      64. Medication.ingredient.strength[x]:strengthRatio.denominator.system
      Definition

      URI que identifica el sistema de codificación de unidades de medida utilizado para codificar la unidad del denominador en la proporción que representa la concentración del principio activo en el medicamento reportado en las notificaciones FACEDRA, utilizando las unidades de medida estándar definidas en el sistema de codificación WHODrug para facilitar la normalización y análisis de los datos de medicamentos en las notificaciones FACEDRA.

      ShortURI del sistema de unidades para el denominador
      Control1..?
      Pattern Valuehttp://unitsofmeasure.org
      66. Medication.ingredient.strength[x]:strengthRatio.denominator.code
      Definition

      Código de la unidad de medida del denominador en la proporción que representa la concentración del principio activo en el medicamento reportado en las notificaciones FACEDRA, utilizando las unidades de medida estándar definidas en el sistema de codificación WHODrug para facilitar la normalización y análisis de los datos de medicamentos en las notificaciones FACEDRA.

      ShortCódigo de la unidad del denominador
      Control1..?
      68. Medication.batch
      Definition

      Información sobre el lote y la fecha de caducidad del medicamento reportado en las notificaciones FACEDRA, para facilitar la normalización y análisis de los datos de medicamentos en las notificaciones FACEDRA, así como para apoyar la identificación de posibles problemas relacionados con lotes específicos de medicamentos en las notificaciones FACEDRA.

      ShortInformación de lote y caducidad del medicamento
      70. Medication.batch.lotNumber
      Definition

      Número de lote del medicamento reportado en las notificaciones FACEDRA, impreso en el empaque, para facilitar la identificación y seguimiento de lotes específicos en las notificaciones FACEDRA.

      ShortNúmero de lote impreso en el empaque
      72. Medication.batch.expirationDate
      Definition

      Fecha de caducidad del medicamento reportado en las notificaciones FACEDRA, en formato MM/AAAA, para facilitar la identificación y seguimiento de la validez de los medicamentos en las notificaciones FACEDRA.

      ShortFecha de caducidad (formato MM/AAAA)

      Guidance on how to interpret the contents of this table can be foundhere

      0. Medication
      Definition

      This resource is primarily used for the identification and definition of a medication, including ingredients, for the purposes of prescribing, dispensing, and administering a medication as well as for making statements about medication use.

      ShortDefinition of a Medication
      Control0..*
      Is Modifierfalse
      Must Supportfalse
      Summaryfalse
      Invariantsdom-2: If the resource is contained in another resource, it SHALL NOT contain nested Resources (contained.contained.empty())
      dom-3: If the resource is contained in another resource, it SHALL be referred to from elsewhere in the resource or SHALL refer to the containing resource (contained.where((('#'+id in (%resource.descendants().reference | %resource.descendants().ofType(canonical) | %resource.descendants().ofType(uri) | %resource.descendants().ofType(url))) or descendants().where(reference = '#').exists() or descendants().where(ofType(canonical) = '#').exists() or descendants().where(ofType(canonical) = '#').exists()).not()).trace('unmatched', id).empty())
      dom-4: If a resource is contained in another resource, it SHALL NOT have a meta.versionId or a meta.lastUpdated (contained.meta.versionId.empty() and contained.meta.lastUpdated.empty())
      dom-5: If a resource is contained in another resource, it SHALL NOT have a security label (contained.meta.security.empty())
      dom-6: A resource should have narrative for robust management (text.`div`.exists())
      2. Medication.id
      Definition

      The logical id of the resource, as used in the URL for the resource. Once assigned, this value never changes.

      ShortLogical id of this artifact
      Comments

      Within the context of the FHIR RESTful interactions, the resource has an id except for cases like the create and conditional update. Otherwise, the use of the resouce id depends on the given use case.

      Control0..1
      Typeid
      Is Modifierfalse
      Must Supportfalse
      Summarytrue
      4. Medication.meta
      Definition

      The metadata about the resource. This is content that is maintained by the infrastructure. Changes to the content might not always be associated with version changes to the resource.

      ShortMetadata about the resource
      Control0..1
      TypeMeta
      Is Modifierfalse
      Must Supportfalse
      Summarytrue
      Invariantsele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count()))
      6. Medication.implicitRules
      Definition

      A reference to a set of rules that were followed when the resource was constructed, and which must be understood when processing the content. Often, this is a reference to an implementation guide that defines the special rules along with other profiles etc.

      ShortA set of rules under which this content was created
      Comments

      Asserting this rule set restricts the content to be only understood by a limited set of trading partners. This inherently limits the usefulness of the data in the long term. However, the existing health eco-system is highly fractured, and not yet ready to define, collect, and exchange data in a generally computable sense. Wherever possible, implementers and/or specification writers should avoid using this element. Often, when used, the URL is a reference to an implementation guide that defines these special rules as part of its narrative along with other profiles, value sets, etc.

      Control0..1
      Typeuri
      Is Modifiertrue because This element is labeled as a modifier because the implicit rules may provide additional knowledge about the resource that modifies its meaning or interpretation
      Primitive ValueThis primitive element may be present, or absent, or replaced by an extension
      Must Supportfalse
      Summarytrue
      Invariantsele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count()))
      8. Medication.language
      Definition

      The base language in which the resource is written.

      ShortLanguage of the resource content
      Comments

      Language is provided to support indexing and accessibility (typically, services such as text to speech use the language tag). The html language tag in the narrative applies to the narrative. The language tag on the resource may be used to specify the language of other presentations generated from the data in the resource. Not all the content has to be in the base language. The Resource.language should not be assumed to apply to the narrative automatically. If a language is specified, it should it also be specified on the div element in the html (see rules in HTML5 for information about the relationship between xml:lang and the html lang attribute).

      Control0..1
      BindingThe codes SHALL be taken from AllLanguages
      (required to http://hl7.org/fhir/ValueSet/all-languages|5.0.0)

      IETF language tag for a human language

      Typecode
      Is Modifierfalse
      Primitive ValueThis primitive element may be present, or absent, or replaced by an extension
      Must Supportfalse
      Summaryfalse
      Invariantsele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count()))
      10. Medication.text
      Definition

      A human-readable narrative that contains a summary of the resource and can be used to represent the content of the resource to a human. The narrative need not encode all the structured data, but is required to contain sufficient detail to make it "clinically safe" for a human to just read the narrative. Resource definitions may define what content should be represented in the narrative to ensure clinical safety.

      ShortText summary of the resource, for human interpretation
      Comments

      Contained resources do not have a narrative. Resources that are not contained SHOULD have a narrative. In some cases, a resource may only have text with little or no additional discrete data (as long as all minOccurs=1 elements are satisfied). This may be necessary for data from legacy systems where information is captured as a "text blob" or where text is additionally entered raw or narrated and encoded information is added later.

      Control0..1
      This element is affected by the following invariants: dom-6
      TypeNarrative
      Is Modifierfalse
      Must Supportfalse
      Summaryfalse
      Alternate Namesnarrative, html, xhtml, display
      Invariantsele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count()))
      12. Medication.contained
      Definition

      These resources do not have an independent existence apart from the resource that contains them - they cannot be identified independently, nor can they have their own independent transaction scope. This is allowed to be a Parameters resource if and only if it is referenced by a resource that provides context/meaning.

      ShortContained, inline Resources
      Comments

      This should never be done when the content can be identified properly, as once identification is lost, it is extremely difficult (and context dependent) to restore it again. Contained resources may have profiles and tags in their meta elements, but SHALL NOT have security labels.

      Control0..*
      This element is affected by the following invariants: dom-2, dom-4, dom-3, dom-5
      TypeResource
      Is Modifierfalse
      Must Supportfalse
      Summaryfalse
      Alternate Namesinline resources, anonymous resources, contained resources
      14. Medication.extension
      Definition

      May be used to represent additional information that is not part of the basic definition of the resource. To make the use of extensions safe and managable, there is a strict set of governance applied to the definition and use of extensions. Though any implementer can define an extension, there is a set of requirements that SHALL be met as part of the definition of the extension.

      ShortAdditional content defined by implementations
      Comments

      There can be no stigma associated with the use of extensions by any application, project, or standard - regardless of the institution or jurisdiction that uses or defines the extensions. The use of extensions is what allows the FHIR specification to retain a core level of simplicity for everyone.

      Control0..*
      TypeExtension
      Is Modifierfalse
      Must Supportfalse
      Summaryfalse
      Alternate Namesextensions, user content
      Invariantsele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count()))
      ext-1: Must have either extensions or value[x], not both (extension.exists() != value.exists())
      16. Medication.modifierExtension
      Definition

      May be used to represent additional information that is not part of the basic definition of the resource and that modifies the understanding of the element that contains it and/or the understanding of the containing element's descendants. Usually modifier elements provide negation or qualification. To make the use of extensions safe and managable, there is a strict set of governance applied to the definition and use of extensions. Though any implementer is allowed to define an extension, there is a set of requirements that SHALL be met as part of the definition of the extension. Applications processing a resource are required to check for modifier extensions.

      Modifier extensions SHALL NOT change the meaning of any elements on Resource or DomainResource (including cannot change the meaning of modifierExtension itself).

      ShortExtensions that cannot be ignored
      Comments

      There can be no stigma associated with the use of extensions by any application, project, or standard - regardless of the institution or jurisdiction that uses or defines the extensions. The use of extensions is what allows the FHIR specification to retain a core level of simplicity for everyone.

      Control0..*
      TypeExtension
      Is Modifiertrue because Modifier extensions are expected to modify the meaning or interpretation of the resource that contains them
      Must Supportfalse
      Summarytrue
      Requirements

      Modifier extensions allow for extensions that cannot be safely ignored to be clearly distinguished from the vast majority of extensions which can be safely ignored. This promotes interoperability by eliminating the need for implementers to prohibit the presence of extensions. For further information, see the definition of modifier extensions.

      Alternate Namesextensions, user content
      Invariantsele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count()))
      ext-1: Must have either extensions or value[x], not both (extension.exists() != value.exists())
      18. Medication.identifier
      Definition

      Business identifier for this medication.

      ShortBusiness identifier for this medication
      Comments

      The serial number could be included as an identifier.

      NoteThis is a business identifier, not a resource identifier (see discussion)
      Control0..*
      TypeIdentifier
      Is Modifierfalse
      Must Supportfalse
      Summarytrue
      Invariantsele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count()))
      20. Medication.code
      Definition

      Nombre comercial del medicamento tal como lo reportó el notificador, junto con su identificación codificada (si está disponible) para facilitar la normalización y análisis de los datos de medicamentos en las notificaciones FACEDRA.

      ShortNombre e identificación del medicamento
      Comments

      Depending on the context of use, the code that was actually selected by the user (prescriber, dispenser, etc.) will have the coding.userSelected set to true. As described in the coding datatype: "A coding may be marked as a "userSelected" if a user selected the particular coded value in a user interface (e.g. the user selects an item in a pick-list). If a user selected coding exists, it is the preferred choice for performing translations etc. Other codes can only be literal translations to alternative code systems, or codes at a lower level of granularity (e.g. a generic code for a vendor-specific primary one).

      Control1..1
      BindingFor example codes, see SNOMEDCTMedicationCodes
      (example to http://hl7.org/fhir/ValueSet/medication-codes|5.0.0)

      A coded concept that defines the type of a medication.

      TypeCodeableConcept
      Is Modifierfalse
      Must Supportfalse
      Summarytrue
      Invariantsele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count()))
      22. Medication.code.id
      Definition

      Unique id for the element within a resource (for internal references). This may be any string value that does not contain spaces.

      ShortUnique id for inter-element referencing
      Control0..1
      This element is affected by the following invariants: ele-1
      Typeid
      Is Modifierfalse
      XML FormatIn the XML format, this property is represented as an attribute.
      Summaryfalse
      24. Medication.code.extension
      Definition

      May be used to represent additional information that is not part of the basic definition of the element. To make the use of extensions safe and managable, there is a strict set of governance applied to the definition and use of extensions. Though any implementer can define an extension, there is a set of requirements that SHALL be met as part of the definition of the extension.

      ShortAdditional content defined by implementations
      Comments

      There can be no stigma associated with the use of extensions by any application, project, or standard - regardless of the institution or jurisdiction that uses or defines the extensions. The use of extensions is what allows the FHIR specification to retain a core level of simplicity for everyone.

      Control0..*
      TypeExtension
      Is Modifierfalse
      Summaryfalse
      Alternate Namesextensions, user content
      Invariantsele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count()))
      ext-1: Must have either extensions or value[x], not both (extension.exists() != value.exists())
      SlicingThis element introduces a set of slices on Medication.code.extension. The slices areUnordered and Open, and can be differentiated using the following discriminators:
      • value @ url
      • 26. Medication.code.coding
        Definition

        Código del medicamento según la clasificación WHODrug, que puede corresponder al principio activo o al producto terminado, para facilitar la normalización y análisis de los datos de medicamentos en las notificaciones FACEDRA.

        ShortCódigo WHODrug del principio activo o producto
        Comments

        Codes may be defined very casually in enumerations, or code lists, up to very formal definitions such as SNOMED CT - see the HL7 v3 Core Principles for more information. Ordering of codings is undefined and SHALL NOT be used to infer meaning. Generally, at most only one of the coding values will be labeled as UserSelected = true.

        Control0..1
        BindingThe codes SHOULD be taken from Medicamentos WHODrug Regional COMISCA
        (preferred to https://hl7.comisca.org/fhir/ValueSet/whoDrug-regional-codes)
        TypeCoding
        Is Modifierfalse
        Summarytrue
        Requirements

        Allows for alternative encodings within a code system, and translations to other code systems.

        Invariantsele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count()))
        28. Medication.code.coding.id
        Definition

        Unique id for the element within a resource (for internal references). This may be any string value that does not contain spaces.

        ShortUnique id for inter-element referencing
        Control0..1
        This element is affected by the following invariants: ele-1
        Typeid
        Is Modifierfalse
        XML FormatIn the XML format, this property is represented as an attribute.
        Summaryfalse
        30. Medication.code.coding.extension
        Definition

        May be used to represent additional information that is not part of the basic definition of the element. To make the use of extensions safe and managable, there is a strict set of governance applied to the definition and use of extensions. Though any implementer can define an extension, there is a set of requirements that SHALL be met as part of the definition of the extension.

        ShortAdditional content defined by implementations
        Comments

        There can be no stigma associated with the use of extensions by any application, project, or standard - regardless of the institution or jurisdiction that uses or defines the extensions. The use of extensions is what allows the FHIR specification to retain a core level of simplicity for everyone.

        Control0..*
        TypeExtension
        Is Modifierfalse
        Summaryfalse
        Alternate Namesextensions, user content
        Invariantsele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count()))
        ext-1: Must have either extensions or value[x], not both (extension.exists() != value.exists())
        SlicingThis element introduces a set of slices on Medication.code.coding.extension. The slices areUnordered and Open, and can be differentiated using the following discriminators:
        • value @ url
        • 32. Medication.code.coding.system
          Definition

          URI que identifica el sistema de codificación WHODrug utilizado para codificar el medicamento en las notificaciones FACEDRA.

          ShortURI del sistema WHODrug
          Comments

          The URI may be an OID (urn:oid:...) or a UUID (urn:uuid:...). OIDs and UUIDs SHALL be references to the HL7 OID registry. Otherwise, the URI should come from HL7's list of FHIR defined special URIs or it should be an absolute reference to some definition that establishes the system clearly and unambiguously.

          Control1..1
          Typeuri
          Is Modifierfalse
          Primitive ValueThis primitive element may be present, or absent, or replaced by an extension
          Summarytrue
          Requirements

          Need to be unambiguous about the source of the definition of the symbol.

          Pattern Valuehttps://hl7.comisca.org/fhir/CodeSystem/whoDrug-regional
          Invariantsele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count()))
          34. Medication.code.coding.version
          Definition

          The version of the code system which was used when choosing this code. Note that a well-maintained code system does not need the version reported, because the meaning of codes is consistent across versions. However this cannot consistently be assured, and when the meaning is not guaranteed to be consistent, the version SHOULD be exchanged.

          ShortVersion of the system - if relevant
          Comments

          Where the terminology does not clearly define what string should be used to identify code system versions, the recommendation is to use the date (expressed in FHIR date format) on which that version was officially published as the version date.

          NoteThis is a business version Id, not a resource version Id (see discussion)
          Control0..1
          Typestring
          Is Modifierfalse
          Primitive ValueThis primitive element may be present, or absent, or replaced by an extension
          Summarytrue
          Invariantsele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count()))
          36. Medication.code.coding.code
          Definition

          Código del medicamento según la clasificación WHODrug, que puede corresponder al principio activo o al producto terminado, para facilitar la normalización y análisis de los datos de medicamentos en las notificaciones FACEDRA.

          ShortCódigo WHODrug
          Control1..1
          This element is affected by the following invariants: cod-1
          Typecode
          Is Modifierfalse
          Primitive ValueThis primitive element may be present, or absent, or replaced by an extension
          Summarytrue
          Requirements

          Need to refer to a particular code in the system.

          Invariantsele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count()))
          38. Medication.code.coding.display
          Definition

          Nombre del medicamento según la clasificación WHODrug, que puede corresponder al principio activo o al producto terminado, para facilitar la normalización y análisis de los datos de medicamentos en las notificaciones FACEDRA.

          ShortNombre normalizado (WHODrug)
          Control1..1
          This element is affected by the following invariants: cod-1
          Typestring
          Is Modifierfalse
          Primitive ValueThis primitive element may be present, or absent, or replaced by an extension
          Summarytrue
          Requirements

          Need to be able to carry a human-readable meaning of the code for readers that do not know the system.

          Invariantsele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count()))
          40. Medication.code.coding.userSelected
          Definition

          Indicates that this coding was chosen by a user directly - e.g. off a pick list of available items (codes or displays).

          ShortIf this coding was chosen directly by the user
          Comments

          Amongst a set of alternatives, a directly chosen code is the most appropriate starting point for new translations. There is some ambiguity about what exactly 'directly chosen' implies, and trading partner agreement may be needed to clarify the use of this element and its consequences more completely.

          Control0..1
          Typeboolean
          Is Modifierfalse
          Primitive ValueThis primitive element may be present, or absent, or replaced by an extension
          Summarytrue
          Requirements

          This has been identified as a clinical safety criterium - that this exact system/code pair was chosen explicitly, rather than inferred by the system based on some rules or language processing.

          Invariantsele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count()))
          42. Medication.code.text
          Definition

          Nombre del medicamento tal como lo reportó el notificador, sin normalizar ni codificar, para preservar la información original proporcionada en la notificación FACEDRA.

          ShortNombre tal como lo reportó el notificador (nombre comercial)
          Comments

          Very often the text is the same as a displayName of one of the codings.

          Control1..1
          Typestring
          Is Modifierfalse
          Primitive ValueThis primitive element may be present, or absent, or replaced by an extension
          Summarytrue
          Requirements

          The codes from the terminologies do not always capture the correct meaning with all the nuances of the human using them, or sometimes there is no appropriate code at all. In these cases, the text is used to capture the full meaning of the source.

          Invariantsele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count()))
          44. Medication.status
          Definition

          Estado del medicamento reportado en las notificaciones FACEDRA, que indica si el medicamento está actualmente en uso (active) o si ha sido retirado del mercado o descontinuado (inactive) para facilitar la normalización y análisis de los datos de medicamentos en las notificaciones FACEDRA.

          ShortEstado del medicamento: active | inactive
          Comments

          This status is intended to identify if the medication in a local system is in active use within a drug database or inventory. For example, a pharmacy system may create a new drug file record for a compounded product "ABC Hospital Special Cream" with an active status. At some point in the future, it may be determined that the drug record was created with an error and the status is changed to "entered in error". This status is not intended to specify if a medication is part of a particular formulary. It is possible that the drug record may be referenced by multiple formularies or catalogues and each of those entries would have a separate status.

          Control0..1
          BindingThe codes SHALL be taken from MedicationStatusCodes
          (required to http://hl7.org/fhir/ValueSet/medication-status|5.0.0)

          A coded concept defining if the medication is in active use.

          Typecode
          Is Modifiertrue because This element changes the interpretation of all descriptive attributes.
          Primitive ValueThis primitive element may be present, or absent, or replaced by an extension
          Must Supportfalse
          Summarytrue
          Invariantsele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count()))
          facedra-med-status-activo-inactivo: Cuando se informa status, solo se permiten los valores active o inactive. ($this = 'active' or $this = 'inactive')
          46. Medication.marketingAuthorizationHolder
          Definition

          Laboratorio titular del registro sanitario del medicamento reportado en las notificaciones FACEDRA, para facilitar la identificación y seguimiento de los responsables de la autorización de los medicamentos en las notificaciones FACEDRA.

          ShortLaboratorio titular del registro sanitario
          Control0..1
          TypeReference(Organization)
          Is Modifierfalse
          Must Supportfalse
          Summarytrue
          Invariantsele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count()))
          48. Medication.doseForm
          Definition

          Forma farmacéutica del medicamento reportado en las notificaciones FACEDRA, que describe la presentación física del medicamento (por ejemplo, tableta, cápsula, inyectable, etc.) para facilitar la normalización y análisis de los datos de medicamentos en las notificaciones FACEDRA.

          ShortForma farmacéutica (tableta, cápsula, inyectable, etc.)
          Comments

          When Medication is referenced from MedicationRequest, this is the ordered form. When Medication is referenced within MedicationDispense, this is the dispensed form. When Medication is referenced within MedicationAdministration, this is administered form.

          Control0..1
          BindingFor example codes, see SNOMEDCTFormCodes
          (example to http://hl7.org/fhir/ValueSet/medication-form-codes|5.0.0)

          A coded concept defining the form of a medication.

          TypeCodeableConcept
          Is Modifierfalse
          Must Supportfalse
          Summaryfalse
          Invariantsele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count()))
          50. Medication.doseForm.id
          Definition

          Unique id for the element within a resource (for internal references). This may be any string value that does not contain spaces.

          ShortUnique id for inter-element referencing
          Control0..1
          This element is affected by the following invariants: ele-1
          Typeid
          Is Modifierfalse
          XML FormatIn the XML format, this property is represented as an attribute.
          Summaryfalse
          52. Medication.doseForm.extension
          Definition

          May be used to represent additional information that is not part of the basic definition of the element. To make the use of extensions safe and managable, there is a strict set of governance applied to the definition and use of extensions. Though any implementer can define an extension, there is a set of requirements that SHALL be met as part of the definition of the extension.

          ShortAdditional content defined by implementations
          Comments

          There can be no stigma associated with the use of extensions by any application, project, or standard - regardless of the institution or jurisdiction that uses or defines the extensions. The use of extensions is what allows the FHIR specification to retain a core level of simplicity for everyone.

          Control0..*
          TypeExtension
          Is Modifierfalse
          Summaryfalse
          Alternate Namesextensions, user content
          Invariantsele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count()))
          ext-1: Must have either extensions or value[x], not both (extension.exists() != value.exists())
          SlicingThis element introduces a set of slices on Medication.doseForm.extension. The slices areUnordered and Open, and can be differentiated using the following discriminators:
          • value @ url
          • 54. Medication.doseForm.coding
            Definition

            Código que representa la forma farmacéutica del medicamento reportado en las notificaciones FACEDRA, utilizando un sistema de codificación estándar para facilitar la normalización y análisis de los datos de medicamentos en las notificaciones FACEDRA.

            ShortCódigo de la forma farmacéutica
            Comments

            Codes may be defined very casually in enumerations, or code lists, up to very formal definitions such as SNOMED CT - see the HL7 v3 Core Principles for more information. Ordering of codings is undefined and SHALL NOT be used to infer meaning. Generally, at most only one of the coding values will be labeled as UserSelected = true.

            Control0..1
            TypeCoding
            Is Modifierfalse
            Summarytrue
            Requirements

            Allows for alternative encodings within a code system, and translations to other code systems.

            Invariantsele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count()))
            56. Medication.doseForm.coding.id
            Definition

            Unique id for the element within a resource (for internal references). This may be any string value that does not contain spaces.

            ShortUnique id for inter-element referencing
            Control0..1
            This element is affected by the following invariants: ele-1
            Typeid
            Is Modifierfalse
            XML FormatIn the XML format, this property is represented as an attribute.
            Summaryfalse
            58. Medication.doseForm.coding.extension
            Definition

            May be used to represent additional information that is not part of the basic definition of the element. To make the use of extensions safe and managable, there is a strict set of governance applied to the definition and use of extensions. Though any implementer can define an extension, there is a set of requirements that SHALL be met as part of the definition of the extension.

            ShortAdditional content defined by implementations
            Comments

            There can be no stigma associated with the use of extensions by any application, project, or standard - regardless of the institution or jurisdiction that uses or defines the extensions. The use of extensions is what allows the FHIR specification to retain a core level of simplicity for everyone.

            Control0..*
            TypeExtension
            Is Modifierfalse
            Summaryfalse
            Alternate Namesextensions, user content
            Invariantsele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count()))
            ext-1: Must have either extensions or value[x], not both (extension.exists() != value.exists())
            SlicingThis element introduces a set of slices on Medication.doseForm.coding.extension. The slices areUnordered and Open, and can be differentiated using the following discriminators:
            • value @ url
            • 60. Medication.doseForm.coding.system
              Definition

              The identification of the code system that defines the meaning of the symbol in the code.

              ShortIdentity of the terminology system
              Comments

              The URI may be an OID (urn:oid:...) or a UUID (urn:uuid:...). OIDs and UUIDs SHALL be references to the HL7 OID registry. Otherwise, the URI should come from HL7's list of FHIR defined special URIs or it should be an absolute reference to some definition that establishes the system clearly and unambiguously.

              Control1..1
              Typeuri
              Is Modifierfalse
              Primitive ValueThis primitive element may be present, or absent, or replaced by an extension
              Summarytrue
              Requirements

              Need to be unambiguous about the source of the definition of the symbol.

              Invariantsele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count()))
              62. Medication.doseForm.coding.version
              Definition

              The version of the code system which was used when choosing this code. Note that a well-maintained code system does not need the version reported, because the meaning of codes is consistent across versions. However this cannot consistently be assured, and when the meaning is not guaranteed to be consistent, the version SHOULD be exchanged.

              ShortVersion of the system - if relevant
              Comments

              Where the terminology does not clearly define what string should be used to identify code system versions, the recommendation is to use the date (expressed in FHIR date format) on which that version was officially published as the version date.

              NoteThis is a business version Id, not a resource version Id (see discussion)
              Control0..1
              Typestring
              Is Modifierfalse
              Primitive ValueThis primitive element may be present, or absent, or replaced by an extension
              Summarytrue
              Invariantsele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count()))
              64. Medication.doseForm.coding.code
              Definition

              Código que representa la forma farmacéutica del medicamento reportado en las notificaciones FACEDRA, utilizando un sistema de codificación estándar para facilitar la normalización y análisis de los datos de medicamentos en las notificaciones FACEDRA.

              ShortCódigo de la forma farmacéutica
              Control1..1
              This element is affected by the following invariants: cod-1
              Typecode
              Is Modifierfalse
              Primitive ValueThis primitive element may be present, or absent, or replaced by an extension
              Summarytrue
              Requirements

              Need to refer to a particular code in the system.

              Invariantsele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count()))
              66. Medication.doseForm.coding.display
              Definition

              Nombre de la forma farmacéutica del medicamento reportado en las notificaciones FACEDRA, utilizando un sistema de codificación estándar para facilitar la normalización y análisis de los datos de medicamentos en las notificaciones FACEDRA.

              ShortNombre de la forma farmacéutica
              Control1..1
              This element is affected by the following invariants: cod-1
              Typestring
              Is Modifierfalse
              Primitive ValueThis primitive element may be present, or absent, or replaced by an extension
              Summarytrue
              Requirements

              Need to be able to carry a human-readable meaning of the code for readers that do not know the system.

              Invariantsele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count()))
              68. Medication.doseForm.coding.userSelected
              Definition

              Indicates that this coding was chosen by a user directly - e.g. off a pick list of available items (codes or displays).

              ShortIf this coding was chosen directly by the user
              Comments

              Amongst a set of alternatives, a directly chosen code is the most appropriate starting point for new translations. There is some ambiguity about what exactly 'directly chosen' implies, and trading partner agreement may be needed to clarify the use of this element and its consequences more completely.

              Control0..1
              Typeboolean
              Is Modifierfalse
              Primitive ValueThis primitive element may be present, or absent, or replaced by an extension
              Summarytrue
              Requirements

              This has been identified as a clinical safety criterium - that this exact system/code pair was chosen explicitly, rather than inferred by the system based on some rules or language processing.

              Invariantsele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count()))
              70. Medication.doseForm.text
              Definition

              A human language representation of the concept as seen/selected/uttered by the user who entered the data and/or which represents the intended meaning of the user.

              ShortPlain text representation of the concept
              Comments

              Very often the text is the same as a displayName of one of the codings.

              Control0..1
              Typestring
              Is Modifierfalse
              Primitive ValueThis primitive element may be present, or absent, or replaced by an extension
              Summarytrue
              Requirements

              The codes from the terminologies do not always capture the correct meaning with all the nuances of the human using them, or sometimes there is no appropriate code at all. In these cases, the text is used to capture the full meaning of the source.

              Invariantsele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count()))
              72. Medication.totalVolume
              Definition

              When the specified product code does not infer a package size, this is the specific amount of drug in the product. For example, when specifying a product that has the same strength (For example, Insulin glargine 100 unit per mL solution for injection), this attribute provides additional clarification of the package amount (For example, 3 mL, 10mL, etc.).

              ShortWhen the specified product code does not infer a package size, this is the specific amount of drug in the product
              Control0..1
              TypeQuantity
              Is Modifierfalse
              Must Supportfalse
              Summarytrue
              Invariantsele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count()))
              74. Medication.ingredient
              Definition

              Información detallada sobre el o los principios activos presentes en el medicamento reportado en las notificaciones FACEDRA, incluyendo su identificación codificada (si está disponible), concentración, forma farmacéutica, lote, fecha de caducidad y titular de venta, para facilitar la normalización y análisis de los datos de medicamentos en las notificaciones FACEDRA.

              ShortPrincipio(s) activo(s) del medicamento
              Comments

              The ingredients need not be a complete list. If an ingredient is not specified, this does not indicate whether an ingredient is present or absent. If an ingredient is specified it does not mean that all ingredients are specified. It is possible to specify both inactive and active ingredients.

              Control0..*
              TypeBackboneElement
              Is Modifierfalse
              Must Supportfalse
              Summaryfalse
              Invariantsele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count()))
              76. Medication.ingredient.id
              Definition

              Unique id for the element within a resource (for internal references). This may be any string value that does not contain spaces.

              ShortUnique id for inter-element referencing
              Control0..1
              This element is affected by the following invariants: ele-1
              Typestring
              Is Modifierfalse
              XML FormatIn the XML format, this property is represented as an attribute.
              Summaryfalse
              78. Medication.ingredient.extension
              Definition

              May be used to represent additional information that is not part of the basic definition of the element. To make the use of extensions safe and managable, there is a strict set of governance applied to the definition and use of extensions. Though any implementer can define an extension, there is a set of requirements that SHALL be met as part of the definition of the extension.

              ShortAdditional content defined by implementations
              Comments

              There can be no stigma associated with the use of extensions by any application, project, or standard - regardless of the institution or jurisdiction that uses or defines the extensions. The use of extensions is what allows the FHIR specification to retain a core level of simplicity for everyone.

              Control0..*
              TypeExtension
              Is Modifierfalse
              Summaryfalse
              Alternate Namesextensions, user content
              Invariantsele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count()))
              ext-1: Must have either extensions or value[x], not both (extension.exists() != value.exists())
              80. Medication.ingredient.modifierExtension
              Definition

              May be used to represent additional information that is not part of the basic definition of the element and that modifies the understanding of the element in which it is contained and/or the understanding of the containing element's descendants. Usually modifier elements provide negation or qualification. To make the use of extensions safe and managable, there is a strict set of governance applied to the definition and use of extensions. Though any implementer can define an extension, there is a set of requirements that SHALL be met as part of the definition of the extension. Applications processing a resource are required to check for modifier extensions.

              Modifier extensions SHALL NOT change the meaning of any elements on Resource or DomainResource (including cannot change the meaning of modifierExtension itself).

              ShortExtensions that cannot be ignored even if unrecognized
              Comments

              There can be no stigma associated with the use of extensions by any application, project, or standard - regardless of the institution or jurisdiction that uses or defines the extensions. The use of extensions is what allows the FHIR specification to retain a core level of simplicity for everyone.

              Control0..*
              TypeExtension
              Is Modifiertrue because Modifier extensions are expected to modify the meaning or interpretation of the element that contains them
              Summarytrue
              Requirements

              Modifier extensions allow for extensions that cannot be safely ignored to be clearly distinguished from the vast majority of extensions which can be safely ignored. This promotes interoperability by eliminating the need for implementers to prohibit the presence of extensions. For further information, see the definition of modifier extensions.

              Alternate Namesextensions, user content, modifiers
              Invariantsele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count()))
              ext-1: Must have either extensions or value[x], not both (extension.exists() != value.exists())
              82. Medication.ingredient.item
              Definition

              Identificación codificada del principio activo presente en el medicamento reportado en las notificaciones FACEDRA, utilizando la clasificación WHODrug para facilitar la normalización y análisis de los datos de medicamentos en las notificaciones FACEDRA.

              ShortSustancia activa codificada con WHODrug
              Control1..1
              BindingFor example codes, see SNOMEDCTMedicationCodes
              (example to http://hl7.org/fhir/ValueSet/medication-codes|5.0.0)
              TypeCodeableReference(Substance, Medication)
              Is Modifierfalse
              Must Supportfalse
              Summaryfalse
              Requirements

              The ingredient may reference a substance (for example, amoxicillin) or another medication (for example in the case of a compounded product, Glaxal Base).

              Invariantsele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count()))
              84. Medication.ingredient.item.id
              Definition

              Unique id for the element within a resource (for internal references). This may be any string value that does not contain spaces.

              ShortUnique id for inter-element referencing
              Control0..1
              This element is affected by the following invariants: ele-1
              Typeid
              Is Modifierfalse
              XML FormatIn the XML format, this property is represented as an attribute.
              Summaryfalse
              86. Medication.ingredient.item.extension
              Definition

              May be used to represent additional information that is not part of the basic definition of the element. To make the use of extensions safe and managable, there is a strict set of governance applied to the definition and use of extensions. Though any implementer can define an extension, there is a set of requirements that SHALL be met as part of the definition of the extension.

              ShortAdditional content defined by implementations
              Comments

              There can be no stigma associated with the use of extensions by any application, project, or standard - regardless of the institution or jurisdiction that uses or defines the extensions. The use of extensions is what allows the FHIR specification to retain a core level of simplicity for everyone.

              Control0..*
              TypeExtension
              Is Modifierfalse
              Summaryfalse
              Alternate Namesextensions, user content
              Invariantsele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count()))
              ext-1: Must have either extensions or value[x], not both (extension.exists() != value.exists())
              SlicingThis element introduces a set of slices on Medication.ingredient.item.extension. The slices areUnordered and Open, and can be differentiated using the following discriminators:
              • value @ url
              • 88. Medication.ingredient.item.concept
                Definition

                A reference to a concept - e.g. the information is identified by its general class to the degree of precision found in the terminology.

                ShortReference to a concept (by class)
                Control0..1
                TypeCodeableConcept
                Is Modifierfalse
                Summarytrue
                Invariantsele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count()))
                90. Medication.ingredient.item.concept.id
                Definition

                Unique id for the element within a resource (for internal references). This may be any string value that does not contain spaces.

                ShortUnique id for inter-element referencing
                Control0..1
                This element is affected by the following invariants: ele-1
                Typeid
                Is Modifierfalse
                XML FormatIn the XML format, this property is represented as an attribute.
                Summaryfalse
                92. Medication.ingredient.item.concept.extension
                Definition

                May be used to represent additional information that is not part of the basic definition of the element. To make the use of extensions safe and managable, there is a strict set of governance applied to the definition and use of extensions. Though any implementer can define an extension, there is a set of requirements that SHALL be met as part of the definition of the extension.

                ShortAdditional content defined by implementations
                Comments

                There can be no stigma associated with the use of extensions by any application, project, or standard - regardless of the institution or jurisdiction that uses or defines the extensions. The use of extensions is what allows the FHIR specification to retain a core level of simplicity for everyone.

                Control0..*
                TypeExtension
                Is Modifierfalse
                Summaryfalse
                Alternate Namesextensions, user content
                Invariantsele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count()))
                ext-1: Must have either extensions or value[x], not both (extension.exists() != value.exists())
                SlicingThis element introduces a set of slices on Medication.ingredient.item.concept.extension. The slices areUnordered and Open, and can be differentiated using the following discriminators:
                • value @ url
                • 94. Medication.ingredient.item.concept.coding
                  Definition

                  A reference to a code defined by a terminology system.

                  ShortCode defined by a terminology system
                  Comments

                  Codes may be defined very casually in enumerations, or code lists, up to very formal definitions such as SNOMED CT - see the HL7 v3 Core Principles for more information. Ordering of codings is undefined and SHALL NOT be used to infer meaning. Generally, at most only one of the coding values will be labeled as UserSelected = true.

                  Control0..1
                  TypeCoding
                  Is Modifierfalse
                  Summarytrue
                  Requirements

                  Allows for alternative encodings within a code system, and translations to other code systems.

                  Invariantsele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count()))
                  96. Medication.ingredient.item.concept.coding.id
                  Definition

                  Unique id for the element within a resource (for internal references). This may be any string value that does not contain spaces.

                  ShortUnique id for inter-element referencing
                  Control0..1
                  This element is affected by the following invariants: ele-1
                  Typeid
                  Is Modifierfalse
                  XML FormatIn the XML format, this property is represented as an attribute.
                  Summaryfalse
                  98. Medication.ingredient.item.concept.coding.extension
                  Definition

                  May be used to represent additional information that is not part of the basic definition of the element. To make the use of extensions safe and managable, there is a strict set of governance applied to the definition and use of extensions. Though any implementer can define an extension, there is a set of requirements that SHALL be met as part of the definition of the extension.

                  ShortAdditional content defined by implementations
                  Comments

                  There can be no stigma associated with the use of extensions by any application, project, or standard - regardless of the institution or jurisdiction that uses or defines the extensions. The use of extensions is what allows the FHIR specification to retain a core level of simplicity for everyone.

                  Control0..*
                  TypeExtension
                  Is Modifierfalse
                  Summaryfalse
                  Alternate Namesextensions, user content
                  Invariantsele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count()))
                  ext-1: Must have either extensions or value[x], not both (extension.exists() != value.exists())
                  SlicingThis element introduces a set of slices on Medication.ingredient.item.concept.coding.extension. The slices areUnordered and Open, and can be differentiated using the following discriminators:
                  • value @ url
                  • 100. Medication.ingredient.item.concept.coding.system
                    Definition

                    URI que identifica el sistema de codificación WHODrug utilizado para codificar el principio activo en las notificaciones FACEDRA.

                    ShortURI del sistema WHODrug
                    Comments

                    The URI may be an OID (urn:oid:...) or a UUID (urn:uuid:...). OIDs and UUIDs SHALL be references to the HL7 OID registry. Otherwise, the URI should come from HL7's list of FHIR defined special URIs or it should be an absolute reference to some definition that establishes the system clearly and unambiguously.

                    Control1..1
                    Typeuri
                    Is Modifierfalse
                    Primitive ValueThis primitive element may be present, or absent, or replaced by an extension
                    Summarytrue
                    Requirements

                    Need to be unambiguous about the source of the definition of the symbol.

                    Pattern Valuehttps://hl7.comisca.org/fhir/CodeSystem/whoDrug-regional
                    Invariantsele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count()))
                    102. Medication.ingredient.item.concept.coding.version
                    Definition

                    The version of the code system which was used when choosing this code. Note that a well-maintained code system does not need the version reported, because the meaning of codes is consistent across versions. However this cannot consistently be assured, and when the meaning is not guaranteed to be consistent, the version SHOULD be exchanged.

                    ShortVersion of the system - if relevant
                    Comments

                    Where the terminology does not clearly define what string should be used to identify code system versions, the recommendation is to use the date (expressed in FHIR date format) on which that version was officially published as the version date.

                    NoteThis is a business version Id, not a resource version Id (see discussion)
                    Control0..1
                    Typestring
                    Is Modifierfalse
                    Primitive ValueThis primitive element may be present, or absent, or replaced by an extension
                    Summarytrue
                    Invariantsele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count()))
                    104. Medication.ingredient.item.concept.coding.code
                    Definition

                    A symbol in syntax defined by the system. The symbol may be a predefined code or an expression in a syntax defined by the coding system (e.g. post-coordination).

                    ShortSymbol in syntax defined by the system
                    Control1..1
                    This element is affected by the following invariants: cod-1
                    Typecode
                    Is Modifierfalse
                    Primitive ValueThis primitive element may be present, or absent, or replaced by an extension
                    Summarytrue
                    Requirements

                    Need to refer to a particular code in the system.

                    Invariantsele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count()))
                    106. Medication.ingredient.item.concept.coding.display
                    Definition

                    A representation of the meaning of the code in the system, following the rules of the system.

                    ShortRepresentation defined by the system
                    Control1..1
                    This element is affected by the following invariants: cod-1
                    Typestring
                    Is Modifierfalse
                    Primitive ValueThis primitive element may be present, or absent, or replaced by an extension
                    Summarytrue
                    Requirements

                    Need to be able to carry a human-readable meaning of the code for readers that do not know the system.

                    Invariantsele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count()))
                    108. Medication.ingredient.item.concept.coding.userSelected
                    Definition

                    Indicates that this coding was chosen by a user directly - e.g. off a pick list of available items (codes or displays).

                    ShortIf this coding was chosen directly by the user
                    Comments

                    Amongst a set of alternatives, a directly chosen code is the most appropriate starting point for new translations. There is some ambiguity about what exactly 'directly chosen' implies, and trading partner agreement may be needed to clarify the use of this element and its consequences more completely.

                    Control0..1
                    Typeboolean
                    Is Modifierfalse
                    Primitive ValueThis primitive element may be present, or absent, or replaced by an extension
                    Summarytrue
                    Requirements

                    This has been identified as a clinical safety criterium - that this exact system/code pair was chosen explicitly, rather than inferred by the system based on some rules or language processing.

                    Invariantsele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count()))
                    110. Medication.ingredient.item.concept.text
                    Definition

                    Nombre del principio activo en texto libre, tal como lo reportó el notificador en las notificaciones FACEDRA, para preservar la información original proporcionada y facilitar la normalización y análisis de los datos de medicamentos en las notificaciones FACEDRA.

                    ShortNombre de la sustancia en texto libre
                    Comments

                    Very often the text is the same as a displayName of one of the codings.

                    Control0..1
                    Typestring
                    Is Modifierfalse
                    Primitive ValueThis primitive element may be present, or absent, or replaced by an extension
                    Summarytrue
                    Requirements

                    The codes from the terminologies do not always capture the correct meaning with all the nuances of the human using them, or sometimes there is no appropriate code at all. In these cases, the text is used to capture the full meaning of the source.

                    Invariantsele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count()))
                    112. Medication.ingredient.item.reference
                    Definition

                    A reference to a resource the provides exact details about the information being referenced.

                    ShortReference to a resource (by instance)
                    Control0..1
                    TypeReference
                    Is Modifierfalse
                    Summarytrue
                    Invariantsele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count()))
                    114. Medication.ingredient.isActive
                    Definition

                    Indication of whether this ingredient affects the therapeutic action of the drug.

                    ShortActive ingredient indicator
                    Control0..1
                    Typeboolean
                    Is Modifierfalse
                    Primitive ValueThis primitive element may be present, or absent, or replaced by an extension
                    Must Supportfalse
                    Summaryfalse
                    Requirements

                    True indicates that the ingredient affects the therapeutic action of the drug (i.e. active). False indicates that the ingredient does not affect the therapeutic action of the drug (i.e. inactive).

                    Invariantsele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count()))
                    116. Medication.ingredient.strength[x]
                    Definition

                    Specifies how many (or how much) of the items there are in this Medication. For example, 250 mg per tablet. This is expressed as a ratio where the numerator is 250mg and the denominator is 1 tablet but can also be expressed a quantity when the denominator is assumed to be 1 tablet.

                    ShortQuantity of ingredient present
                    Control0..1
                    BindingThe codes SHOULD be taken from MedicationIngredientStrengthCodes
                    (preferred to http://hl7.org/fhir/ValueSet/medication-ingredientstrength|5.0.0)

                    A coded concpet defining the strength of an ingredient.

                    TypeChoice of: Ratio, CodeableConcept, Quantity
                    [x] NoteSeeChoice of Data Typesfor further information about how to use [x]
                    Is Modifierfalse
                    Must Supportfalse
                    Summaryfalse
                    Invariantsele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count()))
                    SlicingThis element introduces a set of slices on Medication.ingredient.strength[x]. The slices areUnordered and Open, and can be differentiated using the following discriminators:
                    • type @ $this
                    • 118. Medication.ingredient.strength[x]:strengthRatio
                      Slice NamestrengthRatio
                      Definition

                      Concentración del principio activo presente en el medicamento reportado en las notificaciones FACEDRA, expresada como una proporción (numerador/denominador) para facilitar la normalización y análisis de los datos de medicamentos en las notificaciones FACEDRA.

                      ShortConcentración del ingrediente activo
                      Control0..1
                      TypeRatio
                      [x] NoteSeeChoice of Data Typesfor further information about how to use [x]
                      Is Modifierfalse
                      Must Supportfalse
                      Summaryfalse
                      Invariantsele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count()))
                      120. Medication.ingredient.strength[x]:strengthRatio.id
                      Definition

                      Unique id for the element within a resource (for internal references). This may be any string value that does not contain spaces.

                      ShortUnique id for inter-element referencing
                      Control0..1
                      This element is affected by the following invariants: ele-1
                      Typeid
                      Is Modifierfalse
                      XML FormatIn the XML format, this property is represented as an attribute.
                      Summaryfalse
                      122. Medication.ingredient.strength[x]:strengthRatio.extension
                      Definition

                      May be used to represent additional information that is not part of the basic definition of the element. To make the use of extensions safe and managable, there is a strict set of governance applied to the definition and use of extensions. Though any implementer can define an extension, there is a set of requirements that SHALL be met as part of the definition of the extension.

                      ShortAdditional content defined by implementations
                      Comments

                      There can be no stigma associated with the use of extensions by any application, project, or standard - regardless of the institution or jurisdiction that uses or defines the extensions. The use of extensions is what allows the FHIR specification to retain a core level of simplicity for everyone.

                      Control0..*
                      TypeExtension
                      Is Modifierfalse
                      Summaryfalse
                      Alternate Namesextensions, user content
                      Invariantsele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count()))
                      ext-1: Must have either extensions or value[x], not both (extension.exists() != value.exists())
                      SlicingThis element introduces a set of slices on Medication.ingredient.strength[x].extension. The slices areUnordered and Open, and can be differentiated using the following discriminators:
                      • value @ url
                      • 124. Medication.ingredient.strength[x]:strengthRatio.numerator
                        Definition

                        Valor numérico del numerador en la proporción que representa la concentración del principio activo en el medicamento reportado en las notificaciones FACEDRA.

                        ShortNumerador de la concentración del principio activo
                        Control1..1
                        This element is affected by the following invariants: rat-1
                        TypeQuantity
                        Is Modifierfalse
                        Summarytrue
                        Invariantsele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count()))
                        126. Medication.ingredient.strength[x]:strengthRatio.numerator.id
                        Definition

                        Unique id for the element within a resource (for internal references). This may be any string value that does not contain spaces.

                        ShortUnique id for inter-element referencing
                        Control0..1
                        This element is affected by the following invariants: ele-1
                        Typeid
                        Is Modifierfalse
                        XML FormatIn the XML format, this property is represented as an attribute.
                        Summaryfalse
                        128. Medication.ingredient.strength[x]:strengthRatio.numerator.extension
                        Definition

                        May be used to represent additional information that is not part of the basic definition of the element. To make the use of extensions safe and managable, there is a strict set of governance applied to the definition and use of extensions. Though any implementer can define an extension, there is a set of requirements that SHALL be met as part of the definition of the extension.

                        ShortAdditional content defined by implementations
                        Comments

                        There can be no stigma associated with the use of extensions by any application, project, or standard - regardless of the institution or jurisdiction that uses or defines the extensions. The use of extensions is what allows the FHIR specification to retain a core level of simplicity for everyone.

                        Control0..*
                        TypeExtension
                        Is Modifierfalse
                        Summaryfalse
                        Alternate Namesextensions, user content
                        Invariantsele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count()))
                        ext-1: Must have either extensions or value[x], not both (extension.exists() != value.exists())
                        SlicingThis element introduces a set of slices on Medication.ingredient.strength[x].numerator.extension. The slices areUnordered and Open, and can be differentiated using the following discriminators:
                        • value @ url
                        • 130. Medication.ingredient.strength[x]:strengthRatio.numerator.value
                          Definition

                          Valor numérico del numerador en la proporción que representa la concentración del principio activo en el medicamento reportado en las notificaciones FACEDRA.

                          ShortValor numérico del numerador
                          Comments

                          The implicit precision in the value should always be honored. Monetary values have their own rules for handling precision (refer to standard accounting text books).

                          Control1..1
                          Typedecimal
                          Is Modifierfalse
                          Primitive ValueThis primitive element may be present, or absent, or replaced by an extension
                          Summarytrue
                          Requirements

                          Precision is handled implicitly in almost all cases of measurement.

                          Invariantsele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count()))
                          132. Medication.ingredient.strength[x]:strengthRatio.numerator.comparator
                          Definition

                          How the value should be understood and represented - whether the actual value is greater or less than the stated value due to measurement issues; e.g. if the comparator is "<" , then the real value is < stated value.

                          Short< | <= | >= | > | ad - how to understand the value
                          Control0..1
                          BindingThe codes SHALL be taken from QuantityComparator
                          (required to http://hl7.org/fhir/ValueSet/quantity-comparator|5.0.0)

                          How the Quantity should be understood and represented.

                          Typecode
                          Is Modifiertrue because This is labeled as "Is Modifier" because the comparator modifies the interpretation of the value significantly. If there is no comparator, then there is no modification of the value
                          Primitive ValueThis primitive element may be present, or absent, or replaced by an extension
                          Summarytrue
                          Requirements

                          Need a framework for handling measures where the value is <5ug/L or >400mg/L due to the limitations of measuring methodology.

                          Meaning if MissingIf there is no comparator, then there is no modification of the value
                          Invariantsele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count()))
                          134. Medication.ingredient.strength[x]:strengthRatio.numerator.unit
                          Definition

                          Unidad de medida del numerador en la proporción que representa la concentración del principio activo en el medicamento reportado en las notificaciones FACEDRA, utilizando las unidades de medida estándar definidas en el sistema de codificación WHODrug para facilitar la normalización y análisis de los datos de medicamentos en las notificaciones FACEDRA.

                          ShortUnidad de medida del numerador
                          Control1..1
                          Typestring
                          Is Modifierfalse
                          Primitive ValueThis primitive element may be present, or absent, or replaced by an extension
                          Summarytrue
                          Requirements

                          There are many representations for units of measure and in many contexts, particular representations are fixed and required. I.e. mcg for micrograms.

                          Invariantsele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count()))
                          136. Medication.ingredient.strength[x]:strengthRatio.numerator.system
                          Definition

                          URI que identifica el sistema de codificación de unidades de medida utilizado para codificar la unidad del numerador en la proporción que representa la concentración del principio activo en el medicamento reportado en las notificaciones FACEDRA, utilizando las unidades de medida estándar definidas en el sistema de codificación WHODrug para facilitar la normalización y análisis de los datos de medicamentos en las notificaciones FACEDRA.

                          ShortURI del sistema de unidades para el numerador
                          Control1..1
                          This element is affected by the following invariants: qty-3
                          Typeuri
                          Is Modifierfalse
                          Primitive ValueThis primitive element may be present, or absent, or replaced by an extension
                          Summarytrue
                          Requirements

                          Need to know the system that defines the coded form of the unit.

                          Pattern Valuehttp://unitsofmeasure.org
                          Invariantsele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count()))
                          138. Medication.ingredient.strength[x]:strengthRatio.numerator.code
                          Definition

                          Código de la unidad de medida del numerador en la proporción que representa la concentración del principio activo en el medicamento reportado en las notificaciones FACEDRA, utilizando las unidades de medida estándar definidas en el sistema de codificación WHODrug para facilitar la normalización y análisis de los datos de medicamentos en las notificaciones FACEDRA.

                          ShortCódigo de la unidad del numerador
                          Comments

                          The preferred system is UCUM, but SNOMED CT can also be used (for customary units) or ISO 4217 for currency. The context of use may additionally require a code from a particular system.

                          Control1..1
                          This element is affected by the following invariants: qty-3
                          Typecode
                          Is Modifierfalse
                          Primitive ValueThis primitive element may be present, or absent, or replaced by an extension
                          Summarytrue
                          Requirements

                          Need a computable form of the unit that is fixed across all forms. UCUM provides this for quantities, but SNOMED CT provides many units of interest.

                          Invariantsele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count()))
                          140. Medication.ingredient.strength[x]:strengthRatio.denominator
                          Definition

                          Valor numérico del denominador en la proporción que representa la concentración del principio activo en el medicamento reportado en las notificaciones FACEDRA.

                          ShortDenominador de la concentración del principio activo
                          Control1..1
                          This element is affected by the following invariants: rat-1
                          TypeQuantity(SimpleQuantity)
                          Is Modifierfalse
                          Summarytrue
                          Invariantsele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count()))
                          142. Medication.ingredient.strength[x]:strengthRatio.denominator.id
                          Definition

                          Unique id for the element within a resource (for internal references). This may be any string value that does not contain spaces.

                          ShortUnique id for inter-element referencing
                          Control0..1
                          This element is affected by the following invariants: ele-1
                          Typeid
                          Is Modifierfalse
                          XML FormatIn the XML format, this property is represented as an attribute.
                          Summaryfalse
                          144. Medication.ingredient.strength[x]:strengthRatio.denominator.extension
                          Definition

                          May be used to represent additional information that is not part of the basic definition of the element. To make the use of extensions safe and managable, there is a strict set of governance applied to the definition and use of extensions. Though any implementer can define an extension, there is a set of requirements that SHALL be met as part of the definition of the extension.

                          ShortAdditional content defined by implementations
                          Comments

                          There can be no stigma associated with the use of extensions by any application, project, or standard - regardless of the institution or jurisdiction that uses or defines the extensions. The use of extensions is what allows the FHIR specification to retain a core level of simplicity for everyone.

                          Control0..*
                          TypeExtension
                          Is Modifierfalse
                          Summaryfalse
                          Alternate Namesextensions, user content
                          Invariantsele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count()))
                          ext-1: Must have either extensions or value[x], not both (extension.exists() != value.exists())
                          SlicingThis element introduces a set of slices on Medication.ingredient.strength[x].denominator.extension. The slices areUnordered and Open, and can be differentiated using the following discriminators:
                          • value @ url
                          • 146. Medication.ingredient.strength[x]:strengthRatio.denominator.value
                            Definition

                            Valor numérico del denominador en la proporción que representa la concentración del principio activo en el medicamento reportado en las notificaciones FACEDRA.

                            ShortValor numérico del denominador
                            Comments

                            The implicit precision in the value should always be honored. Monetary values have their own rules for handling precision (refer to standard accounting text books).

                            Control1..1
                            Typedecimal
                            Is Modifierfalse
                            Primitive ValueThis primitive element may be present, or absent, or replaced by an extension
                            Summarytrue
                            Requirements

                            Precision is handled implicitly in almost all cases of measurement.

                            Invariantsele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count()))
                            148. Medication.ingredient.strength[x]:strengthRatio.denominator.comparator
                            Definition

                            Not allowed to be used in this context

                            Short< | <= | >= | > | ad - how to understand the value
                            Control0..0
                            BindingThe codes SHALL be taken from QuantityComparator
                            (required to http://hl7.org/fhir/ValueSet/quantity-comparator|5.0.0)

                            How the Quantity should be understood and represented.

                            Typecode
                            Is Modifiertrue because This is labeled as "Is Modifier" because the comparator modifies the interpretation of the value significantly. If there is no comparator, then there is no modification of the value
                            Primitive ValueThis primitive element may be present, or absent, or replaced by an extension
                            Summarytrue
                            Requirements

                            Need a framework for handling measures where the value is <5ug/L or >400mg/L due to the limitations of measuring methodology.

                            Meaning if MissingIf there is no comparator, then there is no modification of the value
                            Invariantsele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count()))
                            150. Medication.ingredient.strength[x]:strengthRatio.denominator.unit
                            Definition

                            Unidad de medida del denominador en la proporción que representa la concentración del principio activo en el medicamento reportado en las notificaciones FACEDRA, utilizando las unidades de medida estándar definidas en el sistema de codificación WHODrug para facilitar la normalización y análisis de los datos de medicamentos en las notificaciones FACEDRA.

                            ShortUnidad de medida del denominador
                            Control1..1
                            Typestring
                            Is Modifierfalse
                            Primitive ValueThis primitive element may be present, or absent, or replaced by an extension
                            Summarytrue
                            Requirements

                            There are many representations for units of measure and in many contexts, particular representations are fixed and required. I.e. mcg for micrograms.

                            Invariantsele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count()))
                            152. Medication.ingredient.strength[x]:strengthRatio.denominator.system
                            Definition

                            URI que identifica el sistema de codificación de unidades de medida utilizado para codificar la unidad del denominador en la proporción que representa la concentración del principio activo en el medicamento reportado en las notificaciones FACEDRA, utilizando las unidades de medida estándar definidas en el sistema de codificación WHODrug para facilitar la normalización y análisis de los datos de medicamentos en las notificaciones FACEDRA.

                            ShortURI del sistema de unidades para el denominador
                            Control1..1
                            This element is affected by the following invariants: qty-3
                            Typeuri
                            Is Modifierfalse
                            Primitive ValueThis primitive element may be present, or absent, or replaced by an extension
                            Summarytrue
                            Requirements

                            Need to know the system that defines the coded form of the unit.

                            Pattern Valuehttp://unitsofmeasure.org
                            Invariantsele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count()))
                            154. Medication.ingredient.strength[x]:strengthRatio.denominator.code
                            Definition

                            Código de la unidad de medida del denominador en la proporción que representa la concentración del principio activo en el medicamento reportado en las notificaciones FACEDRA, utilizando las unidades de medida estándar definidas en el sistema de codificación WHODrug para facilitar la normalización y análisis de los datos de medicamentos en las notificaciones FACEDRA.

                            ShortCódigo de la unidad del denominador
                            Comments

                            The preferred system is UCUM, but SNOMED CT can also be used (for customary units) or ISO 4217 for currency. The context of use may additionally require a code from a particular system.

                            Control1..1
                            This element is affected by the following invariants: qty-3
                            Typecode
                            Is Modifierfalse
                            Primitive ValueThis primitive element may be present, or absent, or replaced by an extension
                            Summarytrue
                            Requirements

                            Need a computable form of the unit that is fixed across all forms. UCUM provides this for quantities, but SNOMED CT provides many units of interest.

                            Invariantsele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count()))
                            156. Medication.batch
                            Definition

                            Información sobre el lote y la fecha de caducidad del medicamento reportado en las notificaciones FACEDRA, para facilitar la normalización y análisis de los datos de medicamentos en las notificaciones FACEDRA, así como para apoyar la identificación de posibles problemas relacionados con lotes específicos de medicamentos en las notificaciones FACEDRA.

                            ShortInformación de lote y caducidad del medicamento
                            Control0..1
                            TypeBackboneElement
                            Is Modifierfalse
                            Must Supportfalse
                            Summaryfalse
                            Invariantsele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count()))
                            158. Medication.batch.id
                            Definition

                            Unique id for the element within a resource (for internal references). This may be any string value that does not contain spaces.

                            ShortUnique id for inter-element referencing
                            Control0..1
                            This element is affected by the following invariants: ele-1
                            Typestring
                            Is Modifierfalse
                            XML FormatIn the XML format, this property is represented as an attribute.
                            Summaryfalse
                            160. Medication.batch.extension
                            Definition

                            May be used to represent additional information that is not part of the basic definition of the element. To make the use of extensions safe and managable, there is a strict set of governance applied to the definition and use of extensions. Though any implementer can define an extension, there is a set of requirements that SHALL be met as part of the definition of the extension.

                            ShortAdditional content defined by implementations
                            Comments

                            There can be no stigma associated with the use of extensions by any application, project, or standard - regardless of the institution or jurisdiction that uses or defines the extensions. The use of extensions is what allows the FHIR specification to retain a core level of simplicity for everyone.

                            Control0..*
                            TypeExtension
                            Is Modifierfalse
                            Summaryfalse
                            Alternate Namesextensions, user content
                            Invariantsele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count()))
                            ext-1: Must have either extensions or value[x], not both (extension.exists() != value.exists())
                            162. Medication.batch.modifierExtension
                            Definition

                            May be used to represent additional information that is not part of the basic definition of the element and that modifies the understanding of the element in which it is contained and/or the understanding of the containing element's descendants. Usually modifier elements provide negation or qualification. To make the use of extensions safe and managable, there is a strict set of governance applied to the definition and use of extensions. Though any implementer can define an extension, there is a set of requirements that SHALL be met as part of the definition of the extension. Applications processing a resource are required to check for modifier extensions.

                            Modifier extensions SHALL NOT change the meaning of any elements on Resource or DomainResource (including cannot change the meaning of modifierExtension itself).

                            ShortExtensions that cannot be ignored even if unrecognized
                            Comments

                            There can be no stigma associated with the use of extensions by any application, project, or standard - regardless of the institution or jurisdiction that uses or defines the extensions. The use of extensions is what allows the FHIR specification to retain a core level of simplicity for everyone.

                            Control0..*
                            TypeExtension
                            Is Modifiertrue because Modifier extensions are expected to modify the meaning or interpretation of the element that contains them
                            Summarytrue
                            Requirements

                            Modifier extensions allow for extensions that cannot be safely ignored to be clearly distinguished from the vast majority of extensions which can be safely ignored. This promotes interoperability by eliminating the need for implementers to prohibit the presence of extensions. For further information, see the definition of modifier extensions.

                            Alternate Namesextensions, user content, modifiers
                            Invariantsele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count()))
                            ext-1: Must have either extensions or value[x], not both (extension.exists() != value.exists())
                            164. Medication.batch.lotNumber
                            Definition

                            Número de lote del medicamento reportado en las notificaciones FACEDRA, impreso en el empaque, para facilitar la identificación y seguimiento de lotes específicos en las notificaciones FACEDRA.

                            ShortNúmero de lote impreso en el empaque
                            Control0..1
                            Typestring
                            Is Modifierfalse
                            Primitive ValueThis primitive element may be present, or absent, or replaced by an extension
                            Must Supportfalse
                            Summaryfalse
                            Invariantsele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count()))
                            166. Medication.batch.expirationDate
                            Definition

                            Fecha de caducidad del medicamento reportado en las notificaciones FACEDRA, en formato MM/AAAA, para facilitar la identificación y seguimiento de la validez de los medicamentos en las notificaciones FACEDRA.

                            ShortFecha de caducidad (formato MM/AAAA)
                            Control0..1
                            TypedateTime
                            Is Modifierfalse
                            Primitive ValueThis primitive element may be present, or absent, or replaced by an extension
                            Must Supportfalse
                            Summaryfalse
                            Invariantsele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count()))
                            168. Medication.definition
                            Definition

                            A reference to a knowledge resource that provides more information about this medication.

                            ShortKnowledge about this medication
                            Control0..1
                            TypeReference(MedicationKnowledge)
                            Is Modifierfalse
                            Must Supportfalse
                            Summaryfalse
                            Invariantsele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count()))